Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including T cell activation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including alimentary system; cardiovascular system; hemolymphoid system; placenta; and skin. Used to study Alzheimer's disease and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in multiple sclerosis; primary immunodeficiency disease; and severe combined immunodeficiency. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).

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Gene Ontology Evidence Code Abbreviations:

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