MGI GO Slim Categories
The MGI GO_Slim set is defined using unions and disjunctions of GO
terms, so that the MGI GO_Slim cannot currently be used with the
standard tools (e.g. map2slim script). However, a DAG-Edit readable
file is available for download here.
Tab-delimited file mapping GO_ids to MGI GO_Slim category available for
download here.
File of genes symbols grouped by GO_id available for
download here.
RULES
- "OR" means the union of the genes that are annotated to the
terms
- "EXCLUDING" means the union of all the genes annotated to
the parent term and the other terms of that branch of the vocabulary,
except
the named term
Biological Process
Cellular Component
Molecular Function
Biological Process
1.) cell adhesion
GO:0007155
2.) cell-cell signaling
GO:0007267
3.) cell cycle and proliferation: cell cycle OR cell proliferation
GO:0007049/cell cycle
GO:0008283/cell proliferation
4.) death
GO:0016265
5.) cell organization and biogenesis
GO:0016043
6.) protein metabolism
GO:0019538
7.) DNA metabolism
GO:0006259
8.) RNA metabolism: RNA metabolism OR transcription
GO:0016070/RNA metabolism
GO:0006350/transcription
9.) other metabolic processes: metabolism EXCLUDING (DNA metabolism OR
RNA metabolism OR protein metabolism)
GO:0008152
10.) stress response
GO:0006950
11.) transport
GO:0006810
12.) developmental processes
GO:0007275
13.) signal transduction
GO:0007165
14.) unknown = biological_process unknown
GO:0000004
14.) other biological processes: biological_process EXCLUDING (1-13)
GO:0008150
Cellular Component
1.) non-structural extracellular:
extracellular region EXCLUDING extracellular matrix (sensu Metazoa)
GO:0005576
2.) extracellular matrix (sensu Metazoa)
GO:0005578
3.) plasma membrane
GO:0005886
4.) other membranes: (membrane EXCLUDING plasma membrane) OR
membrane fraction
GO:0016020/membrane
GO:0005624/membrane fraction
5.) cytosol: cytosol OR (sarcoplasm EXCLUDING (sarcoplasmic reticulum
OR junctional membrane complex))
GO:0005829/cytosol
GO:0016528/sarcoplasm
GO:0016529/sarcoplasmic reticulum
GO:0030314/junctional membrane complex
6.) cytoskeleton: cytoskeleton OR microtubule organizing center OR
spindle OR muscle fiber OR cilia OR flagellum (sensu Eukaryota)
GO:0005856/cytoskeleton
GO:0005815/microtubule organizing center
GO:0005819/spindle
GO:0030484/muscle fiber
GO:0009434/flagellum (sensu Eukaryota)
7.) mitochondrion
GO:0005739
8.) ER/Golgi: endoplasmic reticulum OR ER-Golgi intermediate
compartment OR Golgi apparatus OR transport vesicle OR Golgi vesicle OR
sarcoplasmic reticulum
GO:0005783/endoplasmic reticulum
GO:0005793/ER-Golgi intermediate compartment
GO:0005794/Golgi apparatus
GO:0030133/transport vesicle
GO:0005798/Golgi vesicle
GO:0016529/sarcoplasmic reticulum
9.) translational apparatus: eukaryotic 43S pre-initiation complex OR
eukaryotic 48S initiation complex OR eukaryotic translational
initiation factor 2B
complex OR eukaryotic translation initiation factor 4F complex OR
nascent
polypeptide-associated complex OR signal recognition particle (sensu
Eukaryota) OR
ribosome
GO:0016282/eukaryotic 43S pre-initiation complex
GO:0016283/eukaryotic 48S initiation complex
GO:0005851/eukaryotic translation initiation factor 2B complex
GO:0016281/eukaryotic translation initiation factor 4F complex
GO:0005854/nascent polypeptide-associated complex
GO:0005786/signal recognition particle (sensu Eukaryota)
GO:0005840/ribosome
10.) nucleus
GO:0005634
11.)other cytoplasmic organelle: acidocalcisome OR cytoplasmic exosome
OR endosome OR glyoxysome OR lysosome OR peroxisome OR vacuole
GO:0020022/acidocalcisome
GO:0000177/cytoplasmic exosome (RNase complex)
GO:0005768/endosome
GO:0009514/glyoxysome
GO:0005764/lysosome
GO:0005777/peroxisome
GO:0005773/vacuole
12.) unknown = cellular_component unknown
GO:0008372
13.) other cell component: cellular_component EXCLUDING (1-12)
GO:0005575
Molecular Function
Tab-delimited file mapping MGI_ids (genes) to MGI GO_Slim function
category available for download here.
1)
signal transduction activity= signal
transducer
activity GO:0004871 [or]
receptor binding GO:0005102
2)
transporter activity= transporter activity GO:0005215
3)
enzyme regulator activity= enzyme regulator
activity GO:0030234
4)
extracellular structural activity= extracellular
matrix
structural constituent GO:0005201
5)
bone, tooth or skin structural activity=structural
constituent
of bone GO:0008147 [or] structural constituent of tooth enamel
GO:0030345 [or] structural constituent of
epidermis GO:0030280
6)
cytoskeletal activity= structural constituent of
cytoskeleton GO:0005200
[or] cytoskeletal protein binding GO:0008092 [or] motor
activity GO:0003774
7)
transcription regulatory activity= transcription
regulator
activity GO:0030528
8)
translation activity= ribosomal large subunit
binding GO:0043023
[or] ribosomal small subunit binding GO:0043024 [or]
ribosome
binding GO:0043022 [or] triplet codon-amino acid adaptor
activity GO:0030533
9)
chaperone-related activity= chaperone regulator
activity GO:0030188
10)
nucleic acid binding activity= nucleic acid
binding GO:0003676
11)
kinase activity= kinase activity GO:0016301
12)
unknown = molecular_function unknown GO:0005554
13)
other molecular function= molecular_function
EXCLUDING (1-12) GO:0003674