Inbred Strains
of Mice: BT
Inbr. F??. Resistant to teratogenic effects (cleft palate) of cortisone
acetate (1/6) (Kalter 1981). Not related to BT/Os. Possibly extinct.
BT/Os
Inbr: F35 +. Black and tan. Genet:
at
. Origin: One pair of albino mice from dealer in Gifu Prefecture. Inbreeding
started in 1951. Cross made with C57BL/6 in 1954, with subsequent selection
for the black colour (
Tajima, 1968).
Characteristics
High incidence of spontaneous mammary tumours (70%), high incidence of
gastric tumours following methylcholanthrene by gavage (1/5), and highly
sensitive to skin carcinogenesis (Akamatsu and Barton, 1974). (NOTE:
Strain BT/Kt is unrelated to this strain.).
Tajima Y. (1968) Stansardized
nomenclature for inbred strains of mice. Experimental animals in cancer
research. Japanese Cancer Association Gann Monograph 5,
123-128.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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