BXD-

Inbr 30+. Set of 24 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x DBA/2J. BXD-31 has low osmotic fragility of erythrocytes due to variation at a single genetic locus causing up-regulation of K-Cl cotransport which induces cell dehydration, a K+ deficit and resistance to osmotic lysis (Armsby et al, 1996). Maint. by Ty.

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Armsby C. C., Stuarttilley A. K., Alper S. L., and Brugnara C. (1996) Resistance to osmotic lysis in BXD-31 mouse erythrocytes -association with up-regulated K-Cl cotransport. American Journal of Physiology-Cell Physiology 39, C866-C877.

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INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK