Inbred Strains
of Mice: C
Inbr: 124. Genet:
b. Origin: Strong 1920, from a cross of Bagg
albino female x DBA male. Strains C3H, CBA, CHI and C121 originated from
the same cross.
Characteristics
Moderate mammary tumour incidence.
C.B17
Inbr. F55 (1993). Genet. A,b,c. Origin: Developed from the 13th. backcross
of BALB/cxC57BL/Ka-Igh
a/Igh
b to BALB/c by Michael
Potter, NIH, to E. Weiler, ICR in 1964. At ICR the mice were backcrossed
to the BALB/cAnNIcr strain for four more generations by Melvin Bosma.
C.B-Igh
a/Igh
b N17 progeny were then intercrossed
to obtain mice homozygous for Igh
b . In 1970 Bosma gave the
C.B17-Igh
b mice to the Laboratory Animal Facility at the Institute
for Cancer Research at Fox Chase Cancer Center. The strain is now maintained
in an SPF barrier facility. Its characteristics are essentially those
of BALB/c, and its primary use is as a coisogenic control strain for C.B17/Icr-
scid.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK