DH

Inbr 32 (Jah, Aug. 1995). Genet. a, Dh, albino. Origin: Institute of Medical Science, University of Tokyo. C57BL/6xC3H/HeF1 mice from J were crossed with BALB/c-nu/nu once and mice with an albino coat colour were selected, and the nu gene was eliminated. Obtained by Jah in 1986. Carries the dominant hemimelia gene Dh (Green 1989). High incidence of lethality among F1 Dh/+ male mice resulting from a cross between DDD females and DH-Dh/+ males, however, this is not observed in the reciprocal cross (Suto et al, 1996).

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Green M. C. (1989) Catalog of mutant genes and polymorphic loci, in Genetic variants and strains of the laboratory mouse, 2nd ed. (Lyon M. F. and Searle A. G., eds), pp. 12-403. Oxford University Press, Oxford, New York, Tokyo.

Suto J., Wakayama T., Imamura K., Goto S., and Fukuta K. (1996) High lethality of F1 (dh/+) male-mice from the cross between DDD female and Dh (Dh/+) male. Exp. Anim. 45, 99-101.

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INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK