KE

Inbr:F94 (Kw). Genet: a, b, c, P. Origin: Krzanowska 1952, from mice of unknown origin; cross also produced KP.

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Characteristics

Mean litter size 6.1; low percentage of fertilised ova. 17.6% of spermatozoa have abnormal heads, the inheritance of this character being connected to the Y chromosome and may be due to a rel. deficiency of androgens (Bartke and Krzanowska, 1972). Sperm head shape, the level of sperm abnormalities and fertilizing capacity are determined largely autonomously by genes acting in the germ cells. (Krzanowska et al 1991).

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Bartke A. and Krzanowska H. (1972) Spermatogenesis in mouse strains with high and low abnormal spermatazoa. J. Hered. 63, 172-174.

Krzanowska H., Wabik-Sliz B., and Rafinski J. (1991) Phenotype and fertilizing capacity of spermatozoa of chimaeric mice produced from two strains that differ in sperm quality. J. Reprod. Fertil. 91, 667-676.

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INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK