NH

Inbr: F109 (Ao). Dilute spotted. Genet: a, d, p, s. Origin: Strong, from crosses involving CBA, N and JK.

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Characteristics

Low tumour incidence; resistant to induction of leukaemia by Moloney virus (1/9) (Law, 1966b). Nodular hyperplasia and adrenal adenomas in at least 10% of old mice; gonadectomy at 6 weeks enhances adenomas; some obesity; breeding ceases at approximately 9 months.

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Law L. W. (1966b) Transmission studies of a leukemogenic virus, MLV, in mice, in Conference on Murine Leukemia (Rich M. A. and Moloney J. B., eds) National Cancer Institute Monograph 22, .

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INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK