Inbred Strains
of Mice: PHH
Inbr: f95 (wE). Grey. Genet:
a, ln. Origin: Weir, from MacArthur
outbred stock obtained from Butler 1949; b x s inbreeding with selection
for high blood pH (
Weir and Clark, 1955; Wolf, 1959).
Characteristics
Blood pH 7.48 _ 0.004, blood lactic acid 3.6 _ 0.2 umol/ml, CO
2
output 5.90 _ 0.01 mg h
-1 g
-1 body weight, sex ratio
52.8 _ 1.00% males (
Weir, 1962). Overall fertility
low.
Weir J. A.
and Clark R. D. (1955) Production of high and low blood-pH lines of mice
by selection with inbreeding. J. Hered. 46, 125-132.
Weir J. A. (1962) Hereditary
and environmental influences on the sex ratio of PHH and PHL mice. Genetics
47, 881-897.
Wolf H. G. (1959) Blood-pM
differences in two inbred strains of mice. J. Hered. 50,
155-158.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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