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Inbred Strains of Mice: SIM

SIM [Sandos Inbred Mice]

Inbr: F 20 + (?). Albino. Origin: A strain of Swiss mice highly susceptible to Friend virus. Congenic line SIM.R has been developed by backcrossing resistance gene from C57BL/6 (Ware and Axelrad, 1972). (NOTE: This is not the SIMPSON strain.)

Ware L. M. and Axelrad A. A. (1972) Inherited resistance to N- and B-tropic murine leukemia viruses in vitro: evidence that congenic mouse strains SIM and SIM.R differ at the Fv-1 locus. Virology 50, 339-348.

INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK
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