Inbred Strains
of Rats: AUG
Inbr: F85 (Pit).
Colour: Dilute hooded.
Genet: h, p.
Origin: Derived from one of the US "August" sublines in 1951 and distributed
by the Chester Beatty Institute, Pollards Wood, England.
Characteristics
Susceptible to experimental allergic encephalomyelitis (
Hughes and Stedronska 1973). Resistant to the induction
of autoimmune thyroiditis according to Rose (
1975),
but susceptible according to Penhale et al (1975a,b.). Low antibody response
to streptococcal group A carbohydrate; not linked to the MHC (
Stankus and Leslie, 1976). Long gestation period (2/8)
(
Peters 1986)
Hughes
R. A. C. and Stedronska J. (1973) The susceptibility of rat strains to
experimental allergic encephalomyelitis. Immunol. 24,
879-884.
Peters A. (1986) Length
of gestation period in eight inbred strains and three outbred stocks of
rats. Animal Technology 37, 109-112.
Rose N. R. (1975) Differing
responses of inbred rat strains in experimental autoimmune thyroiditis.
Cell. Immunol. 18, 360-364.
Stankus
R. P. and Leslie G. A. (1976) Rat interstrain antibody response and crossidiotypic
specificity. Immunogenet. 3, 65-73.
INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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