CWS

Inbr. F55 (Idr 1991).

Colour: Albino.

Genet. A, B, c, h.

Origin: R Shoji from a cross of an outbred Jcl:SD rat with spontaneous cataract and WKAH inbred rats. Subsequent brother x sister mating with selecting for cataract resulted in all offspring from the 3rd. generation developing cataract accompanied by microphthalmia which can be observed from the day that the eyes open.

---

Characteristics

Examination with a slit-lamp microscope shows an adhesion abnormality of the iris on the outside of the lens in abnormal eyes. The character is caused by a single authsomal recessive gene designated cms (cataract, microphthalmia and posterior synechia) (Shoji et al 1988).

---

Shoji R., Kimura R., Murata Y., and Hanai A. (1988) Report: Establishment of a new mutant strain of congenital cataract and Hereditary clubfoot spontaneously occurred in WKAH/Idr inbred strain. Rat News Lett. 20, 22.

---

INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK