Inbred Strains
of Rats: FCH
Inbr. F15 (1989).
Origin: "Fice Combined Hyperlipidemic strain". Strain developed from outbred
stock by selection for high serum cholesterol.
Characteristics
Now has 212_58 mg/dl total serum cholesterol compared with 47_5 mg/dl in
low cholesterol strain FNL. Develops chronic progressive nephrosis and
hyperproteinuria from about 3 months of age (
Patrono
et al 1989).
Patrono
C., Ghiselli G., Lovisolo P. P. S. P., and Barber B. R. (1989) Contribution.
Rat News Lett. 22, 17-18.
INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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