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Inbred Strains of Rats: HMT

HMT

Inbr. F30 (1979).

Colour: Albino,

Genet. c.

Origin: Outbred Alderley Park (strain 1) inbred since 1964 as "Harwell Mouth Tumour".

Characteristics

About 50% incidence of squamous-cell carcinoma of the mouth late in life. Mean life-span 27-30 months with or without mouth tumours (Hulse 1979, Buckley et al 1980).

Buckley P., Hulse E. V., and Keep B. M. (1980) An inbred strain of rats with a high incidence of squamous-cell carcinomas of the mouth. Brit. J. Cancer 41, 295-301.

Hulse E. V. (1979) Announcement of a new inbred strain. Rat News Lett. 5, 40.

INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK
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