Inbred Strains
of Rats: IR
Inbr.F20+?.
Colour: Pale cinnamon beige hooded.
Genet: a, h, cd, ?.
Origin: Harrington 1962 from a cross of a Michigan and a Berlin stock
(Harrington 1981).
Characteristics
Vigorous and healthy, but high incidence of physical anormalities. Skulls
of young fragile through weaning. High death rate from hemorrhage due
to blood platelet disease (
Harrington 1981).
Long latency to emerge into familiar environment (12/12 males, 10/12 females)
(
Harrington 1971a). High open field exploration
in females (3/12) (
Harrington 1972). Low
wheel activity (11/12 males 10/12 females) (
Harrington
1971b).
Harrington
G. M. (1971a) Strain differences among rats initiating exploration of
differing environments. Psychon. Sci. 23, 348-349.
Harrington
G. M. (1971b) Strain differences in rotating wheel activity of the rat.
Psychon. Sci. 23, 363-364.
Harrington
G. M. (1972) Strain differences in open-field behavior of the rat. Psychon.
Sci. 27, 51-53.
Harrington
G. M. (1981) The Har strains of rats: Origins and characteristics. Behav.
Genet. 11, 445-467.
INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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