Krt24 MGI Mouse Gene Detail - MGI:1922956

Symbol

Krt24
Name

keratin 24
Synonyms

2310058N18Rik, 2310075C18Rik

Feature Type

protein coding gene
IDs

MGI:1922956
NCBI Gene: 75706
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr11:99170785-99176088 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 62.92 cM, cytoband D
Mapping Data

2 experiments

SNPs within 2kb

241 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922956	protein coding gene	Chr11:99170785-99176088 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019086	protein coding gene	Chr11:101933312-101941058 (-)
A/J	MGP_AJ_G0019054	protein coding gene	Chr11:97644505-97649745 (-)
AKR/J	MGP_AKRJ_G0019024	protein coding gene	Chr11:100672536-100677739 (-)
BALB/cJ	MGP_BALBcJ_G0019028	protein coding gene	Chr11:98141697-98149380 (-)
C3H/HeJ	MGP_C3HHeJ_G0018841	protein coding gene	Chr11:100828906-100834645 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019479	protein coding gene	Chr11:105063900-105070165 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017111	protein coding gene	Chr11:95205755-95210885 (-)
CAST/EiJ	MGP_CASTEiJ_G0018396	protein coding gene	Chr11:101813631-101819339 (-)
CBA/J	MGP_CBAJ_G0018812	protein coding gene	Chr11:109439335-109444596 (-)
DBA/2J	MGP_DBA2J_G0018920	protein coding gene	Chr11:97206348-97212030 (-)
FVB/NJ	MGP_FVBNJ_G0018909	protein coding gene	Chr11:96723011-96728228 (-)
LP/J	MGP_LPJ_G0018990	protein coding gene	Chr11:102400660-102406954 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018936	protein coding gene	Chr11:109129289-109134524 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019519	protein coding gene	Chr11:101033541-101039771 (-)
PWK/PhJ	MGP_PWKPhJ_G0018167	protein coding gene	Chr11:98280507-98286211 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0017955	protein coding gene	Chr11:100791975-100797518 (-)
WSB/EiJ	MGP_WSBEiJ_G0018444	protein coding gene	Chr11:101005385-101011849 (-)

Human Ortholog

KRT24, keratin 24

Vertebrate Orthologs

12

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

KRT24, keratin 24
Synonyms

CK-24, K24, KA24
Links

HGNC:18527

NCBI Gene ID: 192666

neXtProt AC: NX_Q2M2I5

UniProt: Q2M2I5
Chr Location

17q21.2; chr17:40697991-40703752 (-) GRCh38

MGI Vertebrate Homology

Krt24 stringent orthology
1 human;1 mouse;1 rat;10 zebrafish
HCOP

vertebrate homology predictions: KRT24
Gene Tree

Krt24

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Phenotype Summary

11 phenotype references

All Mutations and Alleles

6
Endonuclease-mediated

3
Gene trapped

1
Targeted

2
Genomic Mutations

2 involving Krt24
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

16 strains or lines available

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All GO Annotations

5
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

7
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

34
RefSeq

2
UniProt

3
CCDS

CCDS36305.1

Ensembl

ENSMUSG00000020913 (Evidence)
NCBI Gene

75706

			Length	Strain/Species	Flank
genomic	75706	NCBI Gene Model \| MGI Sequence Detail	5304	C57BL/6J	± kb
transcript	NM_029393	RefSeq \| MGI Sequence Detail	1863	C57BL/6
polypeptide	A1L317	UniProt \| EBI \| MGI Sequence Detail	512	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000009463 keratin, type I cytoskeletal 24

(term hierarchy)
InterPro Domains

IPR039008 Intermediate filament, rod domain

IPR002957 Keratin, type I

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All nucleic 7

cDNA 7

Microarray probesets 2

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MGI:1916932

Summaries

All 33

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 11
Earliest

J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Krt24:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr110643	Chr11:99176086-99176090 (-)	0 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24