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Garin5a Gene Detail
Summary
  • Symbol
    Garin5a
  • Name
    golgi associated RAB2 interactor 5A
  • Synonyms
    0610007G24Rik, 1700021N13Rik, 1700021P22Rik, Fam71e1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922788
    NCBI Gene: 75538
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44146005-44150910 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 28.83 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922788
 protein coding gene Chr7:44145923-44153690 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032165
 protein coding gene Chr7:44670159-44675393 (+)
A/J MGP_AJ_G0032144
 protein coding gene Chr7:43852908-43857815 (+)
AKR/J MGP_AKRJ_G0032080
 protein coding gene Chr7:45055423-45060536 (+)
BALB/cJ MGP_BALBcJ_G0032156
 protein coding gene Chr7:43848994-43853904 (+)
C3H/HeJ MGP_C3HHeJ_G0031872
 protein coding gene Chr7:45546368-45552460 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032648
 protein coding gene Chr7:46928201-46933108 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029662
 protein coding gene Chr7:46437749-46443154 (+)
CAST/EiJ MGP_CASTEiJ_G0031200
 protein coding gene Chr7:36923354-36928282 (+)
CBA/J MGP_CBAJ_G0031836
 protein coding gene Chr7:48455630-48463035 (+)
DBA/2J MGP_DBA2J_G0031994
 protein coding gene Chr7:43526393-43532142 (+)
FVB/NJ MGP_FVBNJ_G0031945
 protein coding gene Chr7:43266003-43270452 (+)
LP/J MGP_LPJ_G0032072
 protein coding gene Chr7:45352918-45357837 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031982
 protein coding gene Chr7:47201480-47208144 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032664
 protein coding gene Chr7:44271887-44276799 (+)
PWK/PhJ MGP_PWKPhJ_G0030923
 protein coding gene Chr7:36874827-36879804 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030760
 protein coding gene Chr7:32279986-32284846 (+)
WSB/EiJ MGP_WSBEiJ_G0031317
 protein coding gene Chr7:44734289-44739185 (+)



Homology
more
  • Human Ortholog
    GARIN5A, golgi associated RAB2 interactor 5A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GARIN5A, golgi associated RAB2 interactor 5A
  • Synonyms
    FAM71E1, GARIL5
  • Links
    NCBI Gene ID: 112703
    neXtProt AC: NX_Q6IPT2
    UniProt: Q6IPT2

  • Chr Location
    19q13.33; chr19:50466785-50476848 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males are subfertile, with impaired sperm motility, abnormal sperm head morphology, and impaired zona pellucida penetration during in vitro fertilization.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    42
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051113 Ensembl Gene Model | MGI Sequence Detail 4906 C57BL/6J ±  kb
    transcript ENSMUST00000205359 Ensembl | MGI Sequence Detail 1307 Not Applicable  
    polypeptide ENSMUSP00000145700 Ensembl | MGI Sequence Detail 272 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • InterPro Domains
      IPR022168 Golgi associated RAB2 interactor protein-like, Rab2B-binding domain
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 42

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1919501, MGI:1925546, MGI:6885579
    References
    more
    • Summaries
      All 29
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:350937 Wang H, et al., Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS Genet. 2024 Jun;20(6):e1011337
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory