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Arhgap27 Gene Detail
Summary
  • Symbol
    Arhgap27
  • Name
    Rho GTPase activating protein 27
  • Synonyms
    2310069I04Rik, 5730442P18Rik, Sh3d20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916903
    NCBI Gene: 544817
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:103222323-103254518 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 67.02 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    984 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916903
 protein coding gene Chr11:103222310-103254518 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019262
 protein coding gene Chr11:106398214-106430552 (-)
A/J MGP_AJ_G0019230
 protein coding gene Chr11:101882659-101916529 (-)
AKR/J MGP_AKRJ_G0019199
 protein coding gene Chr11:105021913-105056462 (-)
BALB/cJ MGP_BALBcJ_G0019204
 protein coding gene Chr11:102349329-102381551 (-)
C3H/HeJ MGP_C3HHeJ_G0019013
 protein coding gene Chr11:105248715-105280656 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019653
 protein coding gene Chr11:109698459-109735087 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017279
 protein coding gene Chr11:99291494-99323539 (-)
CAST/EiJ MGP_CASTEiJ_G0018567
 protein coding gene Chr11:106239553-106301592 (-)
CBA/J MGP_CBAJ_G0018982
 protein coding gene Chr11:114269251-114301428 (-)
DBA/2J MGP_DBA2J_G0019094
 protein coding gene Chr11:101390236-101422055 (-)
FVB/NJ MGP_FVBNJ_G0019084
 protein coding gene Chr11:100935183-100967630 (-)
LP/J MGP_LPJ_G0019163
 protein coding gene Chr11:106910633-106942780 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019115
 protein coding gene Chr11:113643092-113675373 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019691
 protein coding gene Chr11:105409191-105441562 (-)
PWK/PhJ MGP_PWKPhJ_G0018330
 protein coding gene Chr11:102436949-102498972 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018122
 protein coding gene Chr11:105166404-105200226 (-)
WSB/EiJ MGP_WSBEiJ_G0018616
 protein coding gene Chr11:105409755-105445323 (-)



Homology
more
  • Human Ortholog
    ARHGAP27, Rho GTPase activating protein 27
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP27, Rho GTPase activating protein 27
  • Synonyms
    CAMGAP1, PP905, SH3D20, SH3P20
  • Links
    NCBI Gene ID: 201176
    neXtProt AC: NX_Q6ZUM4
    UniProt: Q6ZUM4

  • Chr Location
    17q21.31; chr17:45393902-45434421 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    840
  • Tissues
    23
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034255 Ensembl Gene Model | MGI Sequence Detail 32196 C57BL/6J ±  kb
transcript ENSMUST00000107024 Ensembl | MGI Sequence Detail 4261 Not Applicable  
polypeptide ENSMUSP00000102639 Ensembl | MGI Sequence Detail 869 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 2
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917809
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:183631 Tossidou I, et al., CD2AP regulates SUMOylation of CIN85 in podocytes. Mol Cell Biol. 2012 Mar;32(6):1068-79
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory