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Ift70a2 Gene Detail
Summary
  • Symbol
    Ift70a2
  • Name
    intraflagellar transport 70A2
  • Synonyms
    OTTMUSG00000015167, Ttc30a2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3700200
    NCBI Gene: 620631
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:75806516-75808523 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 44.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    164 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3700200
 protein coding gene Chr2:75806084-75808523 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025860
 protein coding gene Chr2:76364151-76366015 (-)
A/J MGP_AJ_G0025838
 protein coding gene Chr2:73373682-73379662 (-)
AKR/J MGP_AKRJ_G0025806
 protein coding gene Chr2:75352200-75355251 (-)
BALB/cJ MGP_BALBcJ_G0025831
 protein coding gene Chr2:73510413-73525373 (-)
C3H/HeJ MGP_C3HHeJ_G0025592
 protein coding gene Chr2:75564830-75567294 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026280
 protein coding gene Chr2:78628553-78633565 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023682
 protein coding gene Chr2:70749257-70751745 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0025574
 protein coding gene Chr2:81532854-81540598 (-)
DBA/2J MGP_DBA2J_G0025704
 protein coding gene Chr2:72925945-72929663 (-)
FVB/NJ MGP_FVBNJ_G0025665
 protein coding gene Chr2:72351482-72354034 (-)
LP/J MGP_LPJ_G0025792
 protein coding gene Chr2:76183609-76184793 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025697
 protein coding gene Chr2:83387983-83391203 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026335
 protein coding gene Chr2:75487370-75497994 (-)
PWK/PhJ MGP_PWKPhJ_G0024797
 protein coding gene Chr2:72929988-72938212 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IFT70A, intraflagellar transport 70A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFT70A, intraflagellar transport 70A
  • Synonyms
    CFAP259, FAP259, TTC30A, TTC30B
  • Links
    NCBI Gene ID: 92104
    neXtProt AC: NX_Q86WT1
    UniProt: Q86WT1

  • Chr Location
    2q31.2; chr2:177612999-177618742 (-)  GRCh38
  • Human Ortholog
    IFT70B, intraflagellar transport 70B
  • Synonyms
    fleer, IFT70, TTC30B
  • Links
    NCBI Gene ID: 150737
    neXtProt AC: NX_Q8N4P2
    UniProt: Q8N4P2

  • Chr Location
    2q31.2; chr2:177548998-177552796 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    757
  • Tissues
    15
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 620631 NCBI Gene Model | MGI Sequence Detail 2008 C57BL/6J ±  kb
transcript NM_001081228 RefSeq | MGI Sequence Detail 2008 Not Specified  
polypeptide A2AKQ8 UniProt | EBI | MGI Sequence Detail 664 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000034976 intraflagellar transport protein 70A2
    (term hierarchy)
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019734 Tetratricopeptide repeat
    IPR039941 Tetratricopeptide repeat protein 30
  • GlyGen
    A2AKQ8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:3649606, MGI:7438384
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:100298 Spitz F, et al., Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet. 2005 Aug;37(8):889-93
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory