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Fam209 Gene Detail
Summary
  • Symbol
    Fam209
  • Name
    family with sequence similarity 209
  • Synonyms
    1700029J11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923676
    NCBI Gene: 76426
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:172314474-172316236 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 94.87 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923676
 protein coding gene Chr2:172314440-172316251 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026947
 protein coding gene Chr2:178645066-178646877 (+)
A/J MGP_AJ_G0026914
 protein coding gene Chr2:171168307-171170118 (+)
AKR/J MGP_AKRJ_G0026885
 protein coding gene Chr2:176337608-176339419 (+)
BALB/cJ MGP_BALBcJ_G0026923
 protein coding gene Chr2:171565682-171567493 (+)
C3H/HeJ MGP_C3HHeJ_G0026665
 protein coding gene Chr2:176688156-176689967 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027370
 protein coding gene Chr2:183814789-183816600 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024740
 protein coding gene Chr2:164417005-164418797 (+)
CAST/EiJ MGP_CASTEiJ_G0026123
 protein coding gene Chr2:177360152-177361920 (+)
CBA/J MGP_CBAJ_G0026642
 protein coding gene Chr2:190671030-190672841 (+)
DBA/2J MGP_DBA2J_G0026780
 protein coding gene Chr2:170262262-170264073 (+)
FVB/NJ MGP_FVBNJ_G0026746
 protein coding gene Chr2:168865478-168867289 (+)
LP/J MGP_LPJ_G0026881
 protein coding gene Chr2:178579991-178581802 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026765
 protein coding gene Chr2:193664683-193666494 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027427
 protein coding gene Chr2:176306330-176308141 (+)
PWK/PhJ MGP_PWKPhJ_G0025860
 protein coding gene Chr2:170029709-170031477 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025660
 protein coding gene Chr2:175303330-175305116 (+)
WSB/EiJ MGP_WSBEiJ_G0026196
 protein coding gene Chr2:177279270-177281081 (+)



Homology
more
  • Human Ortholog
    FAM209A, family with sequence similarity 209 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM209A, family with sequence similarity 209 member A
  • Synonyms
    C20orf106, dJ1153D9.3
  • Links
    NCBI Gene ID: 200232
    neXtProt AC: NX_Q5JX71
    UniProt: Q5JX71

  • Chr Location
    20q13.31; chr20:56517187-56533590 (+)  GRCh38
  • Human Ortholog
    FAM209B, family with sequence similarity 209 member B
  • Synonyms
    C20orf107, dJ1153D9.4
  • Links
    NCBI Gene ID: 388799
    neXtProt AC: NX_Q5JX69
    UniProt: Q5JX69

  • Chr Location
    20q13.31; chr20:56533246-56536520 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 3 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility with asthenozoospermia and globozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76426 NCBI Gene Model | MGI Sequence Detail 1763 C57BL/6J ±  kb
    transcript NM_029608 RefSeq | MGI Sequence Detail 649 Not Specified  
    polypeptide A2APA5 UniProt | EBI | MGI Sequence Detail 170 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR027943 FAM209 family
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 4
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:347872 Jin HJ, et al., Disruption in CYLC1 leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice. Elife. 2024 Apr 4;13
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory