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Tyw5 Gene Detail
Summary
  • Symbol
    Tyw5
  • Name
    tRNA-yW synthesizing protein 5
  • Synonyms
    1110034B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915986
    NCBI Gene: 68736
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:57427394-57445833 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 28.78 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    524 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915986
 protein coding gene Chr1:57427394-57446260 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016040
 protein coding gene Chr1:57204429-57224876 (-)
A/J MGP_AJ_G0016023
 protein coding gene Chr1:55210833-55229691 (-)
AKR/J MGP_AKRJ_G0015979
 protein coding gene Chr1:56692245-56712978 (-)
BALB/cJ MGP_BALBcJ_G0015978
 protein coding gene Chr1:55246177-55264985 (-)
C3H/HeJ MGP_C3HHeJ_G0015810
 protein coding gene Chr1:56974563-56993475 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016431
 protein coding gene Chr1:59571894-59590754 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014152
 protein coding gene Chr1:51167668-51185825 (-)
CAST/EiJ MGP_CASTEiJ_G0015392
 protein coding gene Chr1:56236362-56257532 (-)
CBA/J MGP_CBAJ_G0015782
 protein coding gene Chr1:61277904-61298318 (-)
DBA/2J MGP_DBA2J_G0015883
 protein coding gene Chr1:54622704-54642138 (-)
FVB/NJ MGP_FVBNJ_G0015885
 protein coding gene Chr1:53951886-53971010 (-)
LP/J MGP_LPJ_G0015955
 protein coding gene Chr1:58098107-58117079 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015905
 protein coding gene Chr1:64325248-64345137 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016478
 protein coding gene Chr1:56688086-56706942 (-)
PWK/PhJ MGP_PWKPhJ_G0015178
 protein coding gene Chr1:53971520-53990717 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014959
 protein coding gene Chr1:56260382-56279107 (-)
WSB/EiJ MGP_WSBEiJ_G0015455
 protein coding gene Chr1:56363284-56383392 (-)



Homology
more
  • Human Ortholog
    TYW5, tRNA-yW synthesizing protein 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TYW5, tRNA-yW synthesizing protein 5
  • Synonyms
    C2orf60, hTYW5
  • Links
    NCBI Gene ID: 129450
    neXtProt AC: NX_A2RUC4
    UniProt: A2RUC4

  • Chr Location
    2q33.1; chr2:199928913-199955736 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    9
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Tyw5
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    26 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    26
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68736 NCBI Gene Model | MGI Sequence Detail 18440 C57BL/6J ±  kb
transcript NM_001037742 RefSeq | MGI Sequence Detail 1448 C57BL/6  
polypeptide A2RSX7 UniProt | EBI | MGI Sequence Detail 315 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 1
    cDNA 26

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory