Prr16 MGI Mouse Gene Detail - MGI:1918623

Symbol

Prr16
Name

proline rich 16
Synonyms

5430406M13Rik

Feature Type

protein coding gene
IDs

MGI:1918623
NCBI Gene: 71373
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr18:51250970-51437713 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 18, 27.97 cM
Mapping Data

2 experiments

SNPs within 2kb

6534 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918623	protein coding gene	Chr18:51250805-51553116 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024424	protein coding gene	Chr18:50190477-50398630 (+)
A/J	MGP_AJ_G0024390	protein coding gene	Chr18:48248592-48446349 (+)
AKR/J	MGP_AKRJ_G0024360	protein coding gene	Chr18:49610305-49802240 (+)
BALB/cJ	MGP_BALBcJ_G0024390	protein coding gene	Chr18:48418804-48611163 (+)
C3H/HeJ	MGP_C3HHeJ_G0024157	protein coding gene	Chr18:49759190-49961010 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024836	protein coding gene	Chr18:51854998-52077077 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022269	protein coding gene	Chr18:47840525-48029791 (+)
CAST/EiJ	MGP_CASTEiJ_G0023632	protein coding gene	Chr18:49667026-49875134 (+)
CBA/J	MGP_CBAJ_G0024127	protein coding gene	Chr18:53389485-53610180 (+)
DBA/2J	MGP_DBA2J_G0024257	protein coding gene	Chr18:47946081-48134782 (+)
FVB/NJ	MGP_FVBNJ_G0024224	protein coding gene	Chr18:47438787-47625248 (+)
LP/J	MGP_LPJ_G0024342	protein coding gene	Chr18:50216054-50421749 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024254	protein coding gene	Chr18:54996937-55231515 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024883	protein coding gene	Chr18:49596675-49792210 (+)
PWK/PhJ	MGP_PWKPhJ_G0023375	protein coding gene	Chr18:47983148-48180841 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023181	protein coding gene	Chr18:49778189-49989181 (+)
WSB/EiJ	MGP_WSBEiJ_G0023695	protein coding gene	Chr18:49492835-49703523 (+)

Human Ortholog

PRR16, proline rich 16

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PRR16, proline rich 16
Synonyms

DSC54, LARGEN
Links

HGNC:29654

NCBI Gene ID: 51334

neXtProt AC: NX_Q569H4

UniProt: Q569H4
Chr Location

5q23.1; chr5:120464278-120794594 (+) GRCh38

MGI Vertebrate Homology

Prr16 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: PRR16
Gene Tree

Prr16

less

Phenotype Summary

2 phenotype references

All Mutations and Alleles

2
Endonuclease-mediated

1
Spontaneous

1
Genomic Mutations

1 involving Prr16
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

12 strains or lines available

less

All GO Annotations

6
GO References

4

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

11

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

33
RefSeq

2
UniProt

1
CCDS

CCDS37818.1

Ensembl

ENSMUSG00000073565 (Evidence)
NCBI Gene

71373

			Length	Strain/Species	Flank
genomic	71373	NCBI Gene Model \| MGI Sequence Detail	186744	C57BL/6J	± kb
transcript	NM_001081224	RefSeq \| MGI Sequence Detail	2224	Not Specified
polypeptide	A3KMN5	UniProt \| EBI \| MGI Sequence Detail	304	Not Applicable

less

UniProt

1 Sequence
Protein Ontology

PR:000013302 protein Largen

(term hierarchy)
InterPro Domains

IPR027997 Protein Largen/Inhibitory synaptic factor 1

less

All nucleic 13

cDNA 13

Microarray probesets 4

less

MGI:2147247

Summaries

All 26

Gene Ontology 4

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67

TSS for Prr16:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr151038	Chr18:51250747-51250822 (+)	-185 bp
Tssr151039	Chr18:51250826-51250837 (+)	-138 bp
Tssr151040	Chr18:51322276-51322301 (+)	71,319 bp
Tssr151041	Chr18:51364999-51365003 (+)	114,031 bp
Tssr151042	Chr18:51368578-51368579 (+)	117,609 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24