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Rabgap1l Gene Detail
Summary
  • Symbol
    Rabgap1l
  • Name
    RAB GTPase activating protein 1-like
  • Synonyms
    5830411O09Rik, 8430421H08Rik, 9630005B12Rik, Hh1, mKIAA0471
  • Feature Type
    protein coding gene
  • IDs
    MGI:1352507
    NCBI Gene: 29809
  • Alliance
    gene page
  • Transcription Start Sites
    28 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:160046744-160620781 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 69.64 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    11631 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1352507
 protein coding gene Chr1:160046744-160621046 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016643
 protein coding gene Chr1:165412575-166029888 (-)
A/J MGP_AJ_G0016624
 protein coding gene Chr1:158700057-159276153 (-)
AKR/J MGP_AKRJ_G0016590
 protein coding gene Chr1:163544314-164137355 (-)
BALB/cJ MGP_BALBcJ_G0016585
 protein coding gene Chr1:159247243-159821571 (-)
C3H/HeJ MGP_C3HHeJ_G0016409
 protein coding gene Chr1:163731879-164345176 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017046
 protein coding gene Chr1:171025293-171663857 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014755
 protein coding gene Chr1:150849486-151401794 (-)
CAST/EiJ MGP_CASTEiJ_G0015989
 protein coding gene Chr1:163339490-163937502 (-)
CBA/J MGP_CBAJ_G0016384
 protein coding gene Chr1:177094440-177733538 (-)
DBA/2J MGP_DBA2J_G0016490
 protein coding gene Chr1:157673581-158248937 (-)
FVB/NJ MGP_FVBNJ_G0016488
 protein coding gene Chr1:156082322-156659078 (-)
LP/J MGP_LPJ_G0016561
 protein coding gene Chr1:166524079-167127315 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016513
 protein coding gene Chr1:184587748-185297974 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017082
 protein coding gene Chr1:163363546-163957686 (-)
PWK/PhJ MGP_PWKPhJ_G0015775
 protein coding gene Chr1:156817315-157403153 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015562
 protein coding gene Chr1:162212176-162841501 (-)
WSB/EiJ MGP_WSBEiJ_G0016051
 protein coding gene Chr1:163538093-164138914 (-)



Homology
more
  • Human Ortholog
    RABGAP1L, RAB GTPase activating protein 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RABGAP1L, RAB GTPase activating protein 1 like
  • Synonyms
    HHL, TBC1D18
  • Links
    NCBI Gene ID: 9910
    neXtProt AC: NX_B7ZAP0, NX_Q5R372
    UniProt: B7ZAP0, Q5R372

  • Chr Location
    1q25.1; chr1:174159410-174995308 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Mice homozygous for a gene trap insertion are viable, fertile and overtly normal with no alterations in hematopoietic progenitor cell numbers or types.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    30
  • cDNA Data
    92
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026721 Ensembl Gene Model | MGI Sequence Detail 574038 C57BL/6J ±  kb
transcript ENSMUST00000028049 Ensembl | MGI Sequence Detail 2748 Not Applicable  
polypeptide ENSMUSP00000028049 Ensembl | MGI Sequence Detail 815 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 96
    cDNA 94
    Primer pair 2

    Microarray probesets 9
Other
Accession IDs
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MGI:1918728, MGI:1925316, MGI:2138551, MGI:2444195
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:238624 Qu F, et al., Ankyrin-B is a PI3P effector that promotes polarized alpha5beta1-integrin recycling via recruiting RabGAP1L to early endosomes. Elife. 2016 Oct 08;5:e20417
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory