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Sh2d4b Gene Detail
Summary
  • Symbol
    Sh2d4b
  • Name
    SH2 domain containing 4B
  • Synonyms
    A430109M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925182
    NCBI Gene: 328381
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:40535746-40615223 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 22.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2477 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925182
 protein coding gene Chr14:40533478-40624294 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021191
 protein coding gene Chr14:34436006-34515991 (-)
A/J MGP_AJ_G0021139
 protein coding gene Chr14:33103988-33176340 (-)
AKR/J MGP_AKRJ_G0021116
 protein coding gene Chr14:34457746-34537337 (-)
BALB/cJ MGP_BALBcJ_G0021143
 protein coding gene Chr14:33323258-33395796 (-)
C3H/HeJ MGP_C3HHeJ_G0020926
 protein coding gene Chr14:34410893-34491049 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021575
 protein coding gene Chr14:35824334-35910920 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019137
 protein coding gene Chr14:32735102-32810775 (-)
CAST/EiJ MGP_CASTEiJ_G0020451
 protein coding gene Chr14:34184114-34267697 (-)
CBA/J MGP_CBAJ_G0020892
 protein coding gene Chr14:37043572-37127705 (-)
DBA/2J MGP_DBA2J_G0021015
 protein coding gene Chr14:33060254-33130756 (-)
FVB/NJ MGP_FVBNJ_G0020999
 protein coding gene Chr14:32999624-33073426 (-)
LP/J MGP_LPJ_G0021084
 protein coding gene Chr14:34643455-34731513 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021025
 protein coding gene Chr14:36688936-36766254 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021608
 protein coding gene Chr14:34240036-34323636 (-)
PWK/PhJ MGP_PWKPhJ_G0020199
 protein coding gene Chr14:32535506-32610998 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020023
 protein coding gene Chr14:33863399-33946232 (-)
WSB/EiJ MGP_WSBEiJ_G0020506
 protein coding gene Chr14:34343483-34430434 (-)



Homology
more
  • Human Ortholog
    SH2D4B, SH2 domain containing 4B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SH2D4B, SH2 domain containing 4B
  • Links
    NCBI Gene ID: 387694
    neXtProt AC: NX_Q5SQS7
    UniProt: Q5SQS7

  • Chr Location
    10q23.1; chr10:80537902-80646560 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    6
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037833 Ensembl Gene Model | MGI Sequence Detail 79478 C57BL/6J ±  kb
transcript ENSMUST00000096000 Ensembl | MGI Sequence Detail 1597 Not Applicable  
polypeptide ENSMUSP00000093699 Ensembl | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory