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Skint8 Gene Detail
Summary
  • Symbol
    Skint8
  • Name
    selection and upkeep of intraepithelial T cells 8
  • Synonyms
    OTTMUSG00000009475
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651523
    NCBI Gene: 639774
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:111776643-111807558 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 51.53 cM
Strain
Comparison
more
  • SNPs within 2kb
    675 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651523
 protein coding gene Chr4:111776589-111807558 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028582
 protein coding gene Chr4:112777168-112803656 (+)
A/J MGP_AJ_G0028544
 protein coding gene Chr4:108682798-108713203 (+)
AKR/J MGP_AKRJ_G0028491
 protein coding gene Chr4:111410804-111442394 (+)
BALB/cJ MGP_BALBcJ_G0028563
 protein coding gene Chr4:108914814-108942304 (+)
C3H/HeJ MGP_C3HHeJ_G0028277
 protein coding gene Chr4:112126693-112153443 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029004
 protein coding gene Chr4:116850543-116920903 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026294
 protein coding gene Chr4:103859673-103947686 (+)
CAST/EiJ MGP_CASTEiJ_G0027714
 protein coding gene Chr4:110000122-110026905 (+)
CBA/J MGP_CBAJ_G0028246
 protein coding gene Chr4:120651893-120688680 (+)
DBA/2J MGP_DBA2J_G0028394
 protein coding gene Chr4:108339584-108397338 (+)
FVB/NJ MGP_FVBNJ_G0028362
 protein coding gene Chr4:107163021-107187659 (+)
LP/J MGP_LPJ_G0028496
 protein coding gene Chr4:113054993-113081576 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028388
 protein coding gene Chr4:126055679-126092389 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029039
 protein coding gene Chr4:111642451-111671599 (+)
PWK/PhJ MGP_PWKPhJ_G0027440
 protein coding gene Chr4:106589145-106615331 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027264
 protein coding gene Chr4:108989994-109010613 (+)
WSB/EiJ MGP_WSBEiJ_G0027795
 protein coding gene Chr4:111883261-111957331 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    14
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 639774 NCBI Gene Model | MGI Sequence Detail 30916 C57BL/6J ±  kb
transcript NM_001100466 RefSeq | MGI Sequence Detail 1280 C57BL/6  
polypeptide A7XV07 UniProt | EBI | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:323863 McKenzie DR, et al., Normality sensing licenses local T cells for innate-like tissue surveillance. Nat Immunol. 2022 Mar;23(3):411-422
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory