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Nfx1 Gene Detail
Summary
  • Symbol
    Nfx1
  • Name
    nuclear transcription factor, X-box binding 1
  • Synonyms
    1300017N15Rik, 3000003M19Rik, TEG-42, Tex42
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921414
    NCBI Gene: 74164
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:40970906-41025992 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 20.72 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1464 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921414
 protein coding gene Chr4:40970906-41025993 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028152
 protein coding gene Chr4:38887988-38944353 (+)
A/J MGP_AJ_G0028110
 protein coding gene Chr4:37414565-37469738 (+)
AKR/J MGP_AKRJ_G0028073
 protein coding gene Chr4:38372343-38427332 (+)
BALB/cJ MGP_BALBcJ_G0028122
 protein coding gene Chr4:37746067-37801803 (+)
C3H/HeJ MGP_C3HHeJ_G0027850
 protein coding gene Chr4:38913528-38968647 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028563
 protein coding gene Chr4:40314839-40375945 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025904
 protein coding gene Chr4:35067447-35122453 (+)
CAST/EiJ MGP_CASTEiJ_G0027306
 protein coding gene Chr4:38566475-38623461 (+)
CBA/J MGP_CBAJ_G0027822
 protein coding gene Chr4:41692384-41748528 (+)
DBA/2J MGP_DBA2J_G0027966
 protein coding gene Chr4:37333989-37389078 (+)
FVB/NJ MGP_FVBNJ_G0027933
 protein coding gene Chr4:36669281-36724168 (+)
LP/J MGP_LPJ_G0028074
 protein coding gene Chr4:38951681-39006781 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027966
 protein coding gene Chr4:45022448-45079501 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028622
 protein coding gene Chr4:38487365-38544414 (+)
PWK/PhJ MGP_PWKPhJ_G0027025
 protein coding gene Chr4:37339262-37397743 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026852
 protein coding gene Chr4:38180458-38236219 (+)
WSB/EiJ MGP_WSBEiJ_G0027382
 protein coding gene Chr4:38439669-38495928 (+)



Homology
more
  • Human Ortholog
    NFX1, nuclear transcription factor, X-box binding 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NFX1, nuclear transcription factor, X-box binding 1
  • Synonyms
    NFX2, TEG-42, Tex42
  • Links
    NCBI Gene ID: 4799
    neXtProt AC: NX_Q12986
    UniProt: Q12986

  • Chr Location
    9p13.3; chr9:33290512-33371157 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    789
  • Tissues
    34
  • cDNA Data
    21
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74164 NCBI Gene Model | MGI Sequence Detail 55087 C57BL/6J ±  kb
transcript NM_001290449 RefSeq | MGI Sequence Detail 4899 ZRU/MplStud  
polypeptide B1AY10 UniProt | EBI | MGI Sequence Detail 1114 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 21
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1096567, MGI:1913784
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
  • Latest
    J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory