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Mmrn1 Gene Detail
Summary
  • Symbol
    Mmrn1
  • Name
    multimerin 1
  • Synonyms
    4921530G03Rik, Emilin4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918195
    NCBI Gene: 70945
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:60921301-60966362 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 29.22 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1192 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918195
 protein coding gene Chr6:60901960-60966362 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030825
 protein coding gene Chr6:60667965-60746341 (+)
A/J MGP_AJ_G0030792
 protein coding gene Chr6:58015410-58077706 (+)
AKR/J MGP_AKRJ_G0030720
 protein coding gene Chr6:59943471-60008577 (+)
BALB/cJ MGP_BALBcJ_G0030803
 protein coding gene Chr6:58422699-58487179 (+)
C3H/HeJ MGP_C3HHeJ_G0030518
 protein coding gene Chr6:59967629-60032794 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031261
 protein coding gene Chr6:62056398-62126589 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028453
 protein coding gene Chr6:55572068-55636795 (+)
CAST/EiJ MGP_CASTEiJ_G0029915
 protein coding gene Chr6:60048096-60130669 (+)
CBA/J MGP_CBAJ_G0030490
 protein coding gene Chr6:64596581-64665582 (+)
DBA/2J MGP_DBA2J_G0030642
 protein coding gene Chr6:57739791-57807833 (+)
FVB/NJ MGP_FVBNJ_G0030595
 protein coding gene Chr6:57288275-57353586 (+)
LP/J MGP_LPJ_G0030726
 protein coding gene Chr6:60623922-60691294 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030630
 protein coding gene Chr6:67543757-67618378 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031287
 protein coding gene Chr6:59832032-59898046 (+)
PWK/PhJ MGP_PWKPhJ_G0029630
 protein coding gene Chr6:56907645-56967235 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029458
 protein coding gene Chr6:59309734-59370830 (+)
WSB/EiJ MGP_WSBEiJ_G0029997
 protein coding gene Chr6:60132155-60199552 (+)



Homology
more
  • Human Ortholog
    MMRN1, multimerin 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MMRN1, multimerin 1
  • Synonyms
    ECM, EMILIN4, GPIa*, MMRN
  • Links
    NCBI Gene ID: 22915
    neXtProt AC: NX_Q13201
    UniProt: Q13201

  • Chr Location
    4q22.1; chr4:89879511-89954629 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    47 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1024
  • Tissues
    155
  • cDNA Data
    10
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70945 NCBI Gene Model | MGI Sequence Detail 45062 C57BL/6J ±  kb
    transcript NM_027613 RefSeq | MGI Sequence Detail 4636 ZRU/MplStud  
    polypeptide B2RPV6 UniProt | EBI | MGI Sequence Detail 1210 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 80
      Developmental Gene Expression 8
      Diseases 1
      Gene Ontology 8
      Phenotypes 47
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory