Troap Gene Detail

Summary

• Symbol
  Troap
• Name
  trophinin associated protein
• Synonyms
  E130301L11Rik, tastin

• Feature Type
  protein coding gene
• IDs
  MGI:1925983
  NCBI Gene: 78733
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr15:98972854-98981290 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, 55.80 cM, cytoband F3
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  292 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925983	protein coding gene	Chr15:98972456-98981290 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0022321	protein coding gene	Chr15:100880905-100889761 (+)
A/J	MGP_AJ_G0022279	protein coding gene	Chr15:96874513-96884445 (+)
AKR/J	MGP_AKRJ_G0022255	protein coding gene	Chr15:99862372-99870804 (+)
BALB/cJ	MGP_BALBcJ_G0022285	protein coding gene	Chr15:97068059-97076361 (+)
C3H/HeJ	MGP_C3HHeJ_G0022053	protein coding gene	Chr15:99916351-99924765 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022730	protein coding gene	Chr15:104629265-104640789 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020256	protein coding gene	Chr15:92790453-92798868 (+)
CAST/EiJ	MGP_CASTEiJ_G0021577	protein coding gene	Chr15:100771040-100782374 (+)
CBA/J	MGP_CBAJ_G0022022	protein coding gene	Chr15:108186977-108195387 (+)
DBA/2J	MGP_DBA2J_G0022149	protein coding gene	Chr15:96317061-96325591 (+)
FVB/NJ	MGP_FVBNJ_G0022129	protein coding gene	Chr15:95306091-95314524 (+)
LP/J	MGP_LPJ_G0022220	protein coding gene	Chr15:101013579-101022103 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022149	protein coding gene	Chr15:112151370-112162167 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022745	protein coding gene	Chr15:99956234-99964666 (+)
PWK/PhJ	MGP_PWKPhJ_G0021316	protein coding gene	Chr15:96451648-96460685 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0021151	protein coding gene	Chr15:99805374-99814659 (+)
WSB/EiJ	MGP_WSBEiJ_G0021628	protein coding gene	Chr15:100486229-100494477 (+)

Homology

• Human Ortholog
  TROAP, trophinin associated protein

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TROAP, trophinin associated protein
  
• Synonyms
  TASTIN
• Links
  HGNC:12327

  NCBI Gene ID: 10024

  neXtProt AC: NX_Q12815

  UniProt: Q12815

  
  
• Chr Location
  12q13.12; chr12:49323236-49331731 (+)  GRCh38

---

• MGI Vertebrate Homology
  Troap stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: TROAP
• Gene Tree
  Troap
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  22 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  2
• Targeted
  1
• Genomic Mutations
  3 involving Troap
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  20 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  706
• cDNA Data
  5

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN troap

Sequences &
Gene Models

• All Sequences
  49
• RefSeq
  8
• UniProt
  1
• CCDS
  CCDS57008.1

• Ensembl
  ENSMUSG00000032783 (Evidence)
• NCBI Gene
  78733

Representative Sequences			Length	Strain/Species
genomic	78733	NCBI Gene Model | MGI Sequence Detail	8437	C57BL/6J
transcript	NM_030159	RefSeq | MGI Sequence Detail	2280	C57BL/6
polypeptide	B7ZNG4	UniProt | EBI | MGI Sequence Detail	668	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000016691 trophinin-associated protein
  (term hierarchy)
• InterPro Domains
  IPR026133 Tastin

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2146217

References

• Summaries
  All 45

  Diseases 1

  Gene Ontology 2

  Phenotypes 22
• Earliest
  J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
• Latest
  J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

TSS for Troap:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr132990	Chr15:98972849-98972886 (+)	14 bp
Tssr132991	Chr15:98972887-98972903 (+)	41 bp