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Acp4 Gene Detail
Summary
  • Symbol
    Acp4
  • Name
    acid phosphatase 4
  • Synonyms
    Acpt, EG546967
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644563
    NCBI Gene: 100503991
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:43901572-43906802 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 28.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    183 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644563
 protein coding gene Chr7:43901427-43910814 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032156
 protein coding gene Chr7:44399625-44405122 (-)
A/J MGP_AJ_G0032135
 protein coding gene Chr7:43603052-43608484 (-)
AKR/J MGP_AKRJ_G0032071
 protein coding gene Chr7:44796192-44801628 (-)
BALB/cJ MGP_BALBcJ_G0032147
 protein coding gene Chr7:43603663-43607952 (-)
C3H/HeJ MGP_C3HHeJ_G0031863
 protein coding gene Chr7:45288962-45293255 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032639
 protein coding gene Chr7:46649977-46655207 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029647
 protein coding gene Chr7:45514460-45519961 (-)
CAST/EiJ MGP_CASTEiJ_G0031191
 protein coding gene Chr7:36641789-36648051 (-)
CBA/J MGP_CBAJ_G0031827
 protein coding gene Chr7:48156006-48162802 (-)
DBA/2J MGP_DBA2J_G0031985
 protein coding gene Chr7:43275396-43280865 (-)
FVB/NJ MGP_FVBNJ_G0031936
 protein coding gene Chr7:43002572-43009276 (-)
LP/J MGP_LPJ_G0032063
 protein coding gene Chr7:45082379-45088252 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031973
 protein coding gene Chr7:46935826-46940119 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032655
 protein coding gene Chr7:44008366-44015068 (-)
PWK/PhJ MGP_PWKPhJ_G0030914
 protein coding gene Chr7:36611320-36616461 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030751
 protein coding gene Chr7:32020917-32026527 (-)
WSB/EiJ MGP_WSBEiJ_G0031308
 protein coding gene Chr7:44476487-44481555 (-)



Homology
more
  • Human Ortholog
    ACP4, acid phosphatase 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACP4, acid phosphatase 4
  • Synonyms
    ACPT, AI1J
  • Links
    NCBI Gene ID: 93650
    neXtProt AC: NX_Q9BZG2
    UniProt: Q9BZG2

  • Chr Location
    19q13.33; chr19:50790415-50795219 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ACP4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an endonuclease-mediated mutation exhibit chalky-white enamel.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000012777 Ensembl Gene Model | MGI Sequence Detail 5231 C57BL/6J ±  kb
    transcript ENSMUST00000107945 Ensembl | MGI Sequence Detail 1634 Not Applicable  
    polypeptide ENSMUSP00000103578 Ensembl | MGI Sequence Detail 486 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less

    • Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:5906159
    References
    more
    • Summaries
      All 19
      Gene Ontology 6
      Phenotypes 5
    • Earliest
      J:332462 Liang T, et al., Enamel defects in Acp4(R110C/R110C) mice and human ACP4 mutations. Sci Rep. 2022 Oct 1;12(1):16477
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory