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Pttg1ip2 Gene Detail
Summary
  • Symbol
    Pttg1ip2
  • Name
    PTTG1IP family member 2
  • Synonyms
    1700015F17Rik, LOC381716
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686532
    NCBI Gene: 381716
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:5487827-5529143 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 2.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1284 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686532
protein coding gene Chr5:5487827-5529143 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029271
protein coding gene Chr5:2348969-2388352 (-)
A/J MGP_AJ_G0029234
protein coding gene Chr5:2244307-2283279 (-)
AKR/J MGP_AKRJ_G0029184
protein coding gene Chr5:2284184-2328731 (-)
BALB/cJ MGP_BALBcJ_G0029252
protein coding gene Chr5:2450646-2489480 (-)
C3H/HeJ MGP_C3HHeJ_G0028972
protein coding gene Chr5:2485151-2522620 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029702
protein coding gene Chr5:2723264-2765812 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026945
protein coding gene Chr5:2332287-2369162 (-)
CAST/EiJ MGP_CASTEiJ_G0028385
protein coding gene Chr5:2441903-2483014 (-)
CBA/J MGP_CBAJ_G0028933
protein coding gene Chr5:2694611-2738903 (-)
DBA/2J MGP_DBA2J_G0029086
protein coding gene Chr5:2393991-2432177 (-)
FVB/NJ MGP_FVBNJ_G0029047
protein coding gene Chr5:2250303-2288018 (-)
LP/J MGP_LPJ_G0029175
protein coding gene Chr5:2437210-2476259 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029074
protein coding gene Chr5:2612541-2653091 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029733
protein coding gene Chr5:2340828-2383362 (-)
PWK/PhJ MGP_PWKPhJ_G0028107
protein coding gene Chr5:2322659-2361773 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027940
protein coding gene Chr5:2638635-2679022 (-)
WSB/EiJ MGP_WSBEiJ_G0028465
protein coding gene Chr5:2366167-2411302 (-)



Homology
more
  • Human Ortholog
    PTTG1IP2, PTTG1IP family member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTTG1IP2, PTTG1IP family member 2
  • Links
    NCBI Gene ID: 102723899
    UniProt: P0DTF9

  • Chr Location
    chr7:90469639-90513397 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381716 NCBI Gene Model | MGI Sequence Detail 41317 C57BL/6J ±  kb
transcript NM_001200025 RefSeq | MGI Sequence Detail 710 C57BL/6  
polypeptide D3YUK8 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 1
Other
Accession IDs
less
MGI:6407443
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory