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Sirpb1c Gene Detail
Summary
  • Symbol
    Sirpb1c
  • Name
    signal-regulatory protein beta 1C
  • Feature Type
    protein coding gene
  • IDs
    MGI:3807521
    NCBI Gene: 100038947
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:15849311-15902694 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 3.81 cM
Strain
Comparison
more
  • SNPs within 2kb
    221 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3807521
 protein coding gene Chr3:15849309-15902694 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0026794
 protein coding gene Chr3:12813065-13061141 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0024860
 protein coding gene Chr3:11040179-11090242 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026774
 protein coding gene Chr3:13751523-13850822 (-)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0027020
 protein coding gene Chr3:13309898-13358632 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026896
 protein coding gene Chr3:15516047-15562214 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027559
 protein coding gene Chr3:12287558-12522323 (-)
PWK/PhJ MGP_PWKPhJ_G0025986
 protein coding gene Chr3:12313397-12314340 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0026324
 protein coding gene Chr3:12521120-13026697 (-)



Homology
more
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Synonyms
    CD172b, SIRP-BETA-1
  • Links
    NCBI Gene ID: 10326
    neXtProt AC: NX_O00241, NX_Q5TFQ8
    UniProt: O00241, Q5TFQ8

  • Chr Location
    20p13; chr20:1561385-1620061 (-)  GRCh38
  • Human Ortholog
    SIRPG, signal regulatory protein gamma
  • Synonyms
    bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma
  • Links
    NCBI Gene ID: 55423
    neXtProt AC: NX_Q9P1W8
    UniProt: Q9P1W8

  • Chr Location
    20p13; chr20:1629152-1686455 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100038947 NCBI Gene Model | MGI Sequence Detail 53384 C57BL/6J ±  kb
transcript NM_001173459 RefSeq | MGI Sequence Detail 1456 ZRU/MplStud  
polypeptide NP_001166930 RefSeq | MGI Sequence Detail 391 ZRU/MplStud  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4
References
more
  • Summaries
    All 18
    Diseases 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory