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mt-Co2 Gene Detail
Summary
  • Symbol
    mt-Co2
  • Name
    mitochondrially encoded cytochrome c oxidase II
  • Synonyms
    COXII
  • Feature Type
    protein coding gene
  • IDs
    MGI:102503
    NCBI Gene: 17709
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrMT:7013-7696 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome MT, Syntenic
Strain
Comparison
more
  • Strain Annotations
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102503
 protein coding gene ChrMT:7013-7696 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0025807
 protein coding gene Chr2:20892851-20893522 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0025865
 protein coding gene Chr2:20041403-20041979 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    COX2, cytochrome c oxidase subunit II
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX2, cytochrome c oxidase subunit II
  • Synonyms
    COII, MTCO2
  • Links
    NCBI Gene ID: 4513
    neXtProt AC: NX_P00403
    UniProt: P00403

  • Chr Location
    chrMT:7586-8269 (+)  GRCh38
  • Human Ortholog
    MTCO2P12, MT-CO2 pseudogene 12
  • Synonyms
    COII, COX2, COXII, MT-CO2, MTCO2
  • Links
    NCBI Gene ID: 107075310
    UniProt: P00403

  • Chr Location
    1p36.33; chr1:632757-633438 (+)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    20
  • cDNA Data
    10
  • Literature Summary
    15
Sequences &
Gene Models
less
  • All Sequences
    59
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 17709 NCBI Gene Model | MGI Sequence Detail 684 C57BL/6J ±  kb
transcript AF378830 GenBank | ENA | DDBJ | MGI Sequence Detail 725 Not Specified  
polypeptide P00405 UniProt | EBI | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 10
    Primer pair 2
    Other 52

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-19340, MGI:2138430, MGI:2138457
References
more
  • Summaries
    All 53
    Developmental Gene Expression 15
    Gene Ontology 12
  • Earliest
    J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory