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Lmo3 Gene Detail
Summary
  • Symbol
    Lmo3
  • Name
    LIM domain only 3
  • Synonyms
    Rbtn-3, Rbtn3
  • Feature Type
    protein coding gene
  • IDs
    MGI:102810
    NCBI Gene: 109593
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:138339916-138558966 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 69.02 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6062 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102810
 protein coding gene Chr6:138339916-138559204 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031441
 protein coding gene Chr6:142935900-143181213 (-)
A/J MGP_AJ_G0031416
 protein coding gene Chr6:137318253-137536654 (-)
AKR/J MGP_AKRJ_G0031344
 protein coding gene Chr6:141489831-141716922 (-)
BALB/cJ MGP_BALBcJ_G0031423
 protein coding gene Chr6:137167188-137390719 (-)
C3H/HeJ MGP_C3HHeJ_G0031145
 protein coding gene Chr6:141513354-141743257 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031885
 protein coding gene Chr6:146831666-147074060 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029014
 protein coding gene Chr6:136320353-136536017 (-)
CAST/EiJ MGP_CASTEiJ_G0030513
 protein coding gene Chr6:141005329-141245784 (-)
CBA/J MGP_CBAJ_G0031105
 protein coding gene Chr6:152433696-152700082 (-)
DBA/2J MGP_DBA2J_G0031262
 protein coding gene Chr6:136169341-136401228 (-)
FVB/NJ MGP_FVBNJ_G0031213
 protein coding gene Chr6:135020710-135240725 (-)
LP/J MGP_LPJ_G0031346
 protein coding gene Chr6:143073093-143310615 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031253
 protein coding gene Chr6:156226705-156489495 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031917
 protein coding gene Chr6:141227939-141457540 (-)
PWK/PhJ MGP_PWKPhJ_G0030240
 protein coding gene Chr6:134647173-134872031 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030064
 protein coding gene Chr6:139478861-139710068 (-)
WSB/EiJ MGP_WSBEiJ_G0030606
 protein coding gene Chr6:141864071-142111438 (-)



Homology
more
  • Human Ortholog
    LMO3, LIM domain only 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LMO3, LIM domain only 3
  • Synonyms
    RBTN3, RBTNL2, Rhom-3, RHOM3
  • Links
    NCBI Gene ID: 55885
    neXtProt AC: NX_Q8TAP4
    UniProt: Q8TAP4

  • Chr Location
    12p12.3
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    1 phenotype from multigenic genotypes
    7 phenotype references
Homozygous mutant mice show no overt phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    929
  • Tissues
    117
  • cDNA Data
    12
  • Literature Summary
    51
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030226 Ensembl Gene Model | MGI Sequence Detail 219051 C57BL/6J ±  kb
transcript ENSMUST00000163065 Ensembl | MGI Sequence Detail 2425 Not Applicable  
polypeptide ENSMUSP00000124762 Ensembl | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    Genomic 2
    cDNA 13
    Other 8

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13798, MGD-MRK-13801, MGD-MRK-19718, MGI:2141511, MGI:2141726
References
more
  • Summaries
    All 81
    Developmental Gene Expression 51
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:2046 Foroni L, et al., The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development. J Mol Biol. 1992 Aug 5;226(3):747-61
  • Latest
    J:344351 Deska-Gauthier D, et al., Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity. Cell Rep. 2023 Dec 29;43(1):113635
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory