About   Help   FAQ
Ccng1 Gene Detail
Summary
  • Symbol
    Ccng1
  • Name
    cyclin G1
  • Synonyms
    cyclin G
  • Feature Type
    protein coding gene
  • IDs
    MGI:102890
    NCBI Gene: 12450
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:40639379-40646044 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 24.42 cM, cytoband B1.1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    301 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102890
 protein coding gene Chr11:40639379-40646138 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018163
 protein coding gene Chr11:39415047-39421806 (-)
A/J MGP_AJ_G0018136
 protein coding gene Chr11:37922355-37929114 (-)
AKR/J MGP_AKRJ_G0018100
 protein coding gene Chr11:39035151-39041910 (-)
BALB/cJ MGP_BALBcJ_G0018105
 protein coding gene Chr11:38116906-38123665 (-)
C3H/HeJ MGP_C3HHeJ_G0017918
 protein coding gene Chr11:39062136-39068895 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018559
 protein coding gene Chr11:40599834-40606593 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016214
 protein coding gene Chr11:36149262-36156024 (-)
CAST/EiJ MGP_CASTEiJ_G0017482
 protein coding gene Chr11:39090896-39097702 (-)
CBA/J MGP_CBAJ_G0017891
 protein coding gene Chr11:42509327-42516086 (-)
DBA/2J MGP_DBA2J_G0018001
 protein coding gene Chr11:37673393-37680152 (-)
FVB/NJ MGP_FVBNJ_G0017995
 protein coding gene Chr11:37424846-37431605 (-)
LP/J MGP_LPJ_G0018073
 protein coding gene Chr11:39653824-39660583 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018019
 protein coding gene Chr11:43803324-43809922 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018598
 protein coding gene Chr11:39101298-39108057 (-)
PWK/PhJ MGP_PWKPhJ_G0017263
 protein coding gene Chr11:37748807-37755626 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017055
 protein coding gene Chr11:38934524-38941278 (-)
WSB/EiJ MGP_WSBEiJ_G0017531
 protein coding gene Chr11:38823611-38830370 (-)



Homology
more
  • Human Ortholog
    CCNG1, cyclin G1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCNG1, cyclin G1
  • Synonyms
    CCNG
  • Links
    NCBI Gene ID: 900
    neXtProt AC: NX_P51959
    UniProt: P51959

  • Chr Location
    5q34; chr5:163437569-163457640 (+)  GRCh38
Human Diseases
more
  • Diseases
    6 with human CCNG1 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Depending on the allele, homozygous mutants exhibit increased cellular sensitivity to gamma-irradiation or decreased incidence of induced hepatic tumors.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    831
  • Tissues
    69
  • cDNA Data
    24
  • Literature Summary
    41
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12450 NCBI Gene Model | MGI Sequence Detail 6666 C57BL/6J ±  kb
    transcript NM_009831 RefSeq | MGI Sequence Detail 3418 C57BL/6  
    polypeptide P51945 UniProt | EBI | MGI Sequence Detail 294 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      Genomic 4
      cDNA 24
      Primer pair 10
      Other 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-23724, MGI:2144106
    References
    more
    • Summaries
      All 88
      Developmental Gene Expression 41
      Gene Ontology 5
      Phenotypes 17
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:353382 Strasser AS, et al., Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption. Nat Commun. 2024 Aug 21;15(1):7154
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory