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Rsu1 Gene Detail
Summary
  • Symbol
    Rsu1
  • Name
    Ras suppressor protein 1
  • Synonyms
    rsp-1, RsuI
  • Feature Type
    protein coding gene
  • IDs
    MGI:103040
    NCBI Gene: 20163
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:13081778-13276116 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 9.73 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5075 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103040
 protein coding gene Chr2:13081632-13276226 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025354
 protein coding gene Chr2:10554327-10758154 (-)
A/J MGP_AJ_G0025331
 protein coding gene Chr2:10163893-10357625 (-)
AKR/J MGP_AKRJ_G0025300
 protein coding gene Chr2:10455176-10657196 (-)
BALB/cJ MGP_BALBcJ_G0025327
 protein coding gene Chr2:10150872-10348229 (-)
C3H/HeJ MGP_C3HHeJ_G0025087
 protein coding gene Chr2:10399376-10605452 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025769
 protein coding gene Chr2:10837237-11042419 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023184
 protein coding gene Chr2:9771716-9960425 (-)
CAST/EiJ MGP_CASTEiJ_G0024550
 protein coding gene Chr2:10373100-10570550 (-)
CBA/J MGP_CBAJ_G0025066
 protein coding gene Chr2:11322574-11522642 (-)
DBA/2J MGP_DBA2J_G0025198
 protein coding gene Chr2:10059617-10252555 (-)
FVB/NJ MGP_FVBNJ_G0025160
 protein coding gene Chr2:9954798-10148208 (-)
LP/J MGP_LPJ_G0025284
 protein coding gene Chr2:10461512-10666868 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025192
 protein coding gene Chr2:11196346-11399248 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025827
 protein coding gene Chr2:10374110-10573437 (-)
PWK/PhJ MGP_PWKPhJ_G0024301
 protein coding gene Chr2:9952094-10139802 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024101
 protein coding gene Chr2:10411366-10606502 (-)
WSB/EiJ MGP_WSBEiJ_G0024620
 protein coding gene Chr2:10460564-10665687 (-)



Homology
more
  • Human Ortholog
    RSU1, Ras suppressor protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RSU1, Ras suppressor protein 1
  • Synonyms
    RSP-1
  • Links
    NCBI Gene ID: 6251
    neXtProt AC: NX_Q15404
    UniProt: Q15404

  • Chr Location
    10p13; chr10:16590611-16817463 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    8
  • cDNA Data
    123
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20163 NCBI Gene Model | MGI Sequence Detail 194339 C57BL/6J ±  kb
    transcript NM_001420904 RefSeq | MGI Sequence Detail 3078 C57BL/6  
    polypeptide Q01730 UniProt | EBI | MGI Sequence Detail 277 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 124
      cDNA 123
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-23902
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:43405 Cutler ML, et al., Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformation. Mol Cell Biol. 1992 Sep;12(9):3750-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory