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Muc13 Gene Detail
Summary
  • Symbol
    Muc13
  • Name
    mucin 13, epithelial transmembrane
  • Synonyms
    114/A10, Ly64
  • Feature Type
    protein coding gene
  • IDs
    MGI:103190
    NCBI Gene: 17063
  • Alliance
    gene page
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:33614407-33640299 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 24.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    777 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103190
 protein coding gene Chr16:33614407-33640304 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022758
 protein coding gene Chr16:32019821-32050562 (+)
A/J MGP_AJ_G0022723
 protein coding gene Chr16:30481281-30506796 (+)
AKR/J MGP_AKRJ_G0022696
 protein coding gene Chr16:31558632-31588061 (+)
BALB/cJ MGP_BALBcJ_G0022725
 protein coding gene Chr16:30595428-30620733 (+)
C3H/HeJ MGP_C3HHeJ_G0022490
 protein coding gene Chr16:31685017-31712393 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023174
 protein coding gene Chr16:32726755-32758246 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020692
 protein coding gene Chr16:30828228-30853110 (+)
CAST/EiJ MGP_CASTEiJ_G0022018
 protein coding gene Chr16:31861820-31888565 (+)
CBA/J MGP_CBAJ_G0022460
 protein coding gene Chr16:34038751-34078473 (+)
DBA/2J MGP_DBA2J_G0022593
 protein coding gene Chr16:30306318-30331310 (+)
FVB/NJ MGP_FVBNJ_G0022568
 protein coding gene Chr16:30296573-30322943 (+)
LP/J MGP_LPJ_G0022660
 protein coding gene Chr16:31750367-31778104 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022587
 protein coding gene Chr16:33409901-33438376 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023186
 protein coding gene Chr16:31567022-31595779 (+)
PWK/PhJ MGP_PWKPhJ_G0021759
 protein coding gene Chr16:30685435-30711299 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021588
 protein coding gene Chr16:31361343-31389661 (+)
WSB/EiJ MGP_WSBEiJ_G0022062
 protein coding gene Chr16:31531659-31554087 (+)



Homology
more
  • Human Ortholog
    MUC13, mucin 13, cell surface associated
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MUC13, mucin 13, cell surface associated
  • Synonyms
    DRCC1, MUC-13
  • Links
    NCBI Gene ID: 56667
    neXtProt AC: NX_Q9H3R2
    UniProt: Q9H3R2

  • Chr Location
    chr3:124905442-124953819 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased sensitivity to DSS-induced colitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    3
  • cDNA Data
    60
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17063 NCBI Gene Model | MGI Sequence Detail 25893 C57BL/6J ±  kb
    transcript NM_010739 RefSeq | MGI Sequence Detail 2969 C57BL/6  
    polypeptide P19467 UniProt | EBI | MGI Sequence Detail 573 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 61
      cDNA 60
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-24058, MGD-MRK-25625, MGI:2146381
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:9704 Dougherty GJ, et al., Molecular cloning of 114/A10, a cell surface antigen containing highly conserved repeated elements, which is expressed by murine hemopoietic progenitor cells and interleukin-3-dependent cell lines. J Biol Chem. 1989 Apr 15;264(11):6509-14
    • Latest
      J:353621 Patel VN, et al., Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory