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Myef2 Gene Detail
Summary
  • Symbol
    Myef2
  • Name
    myelin basic protein expression factor 2, repressor
  • Synonyms
    mKIAA1341
  • Feature Type
    protein coding gene
  • IDs
    MGI:104592
    NCBI Gene: 17876
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:124926548-124965581 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 61.16 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    855 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104592
 protein coding gene Chr2:124922894-124966727 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026424
 protein coding gene Chr2:128248504-128288018 (-)
A/J MGP_AJ_G0026386
 protein coding gene Chr2:123031399-123071443 (-)
AKR/J MGP_AKRJ_G0026362
 protein coding gene Chr2:126548408-126587862 (-)
BALB/cJ MGP_BALBcJ_G0026398
 protein coding gene Chr2:123322683-123362399 (-)
C3H/HeJ MGP_C3HHeJ_G0026142
 protein coding gene Chr2:127033875-127073337 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026845
 protein coding gene Chr2:132348729-132391403 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024222
 protein coding gene Chr2:117820431-117859267 (-)
CAST/EiJ MGP_CASTEiJ_G0025604
 protein coding gene Chr2:127278905-127318604 (-)
CBA/J MGP_CBAJ_G0026122
 protein coding gene Chr2:137155926-137200086 (-)
DBA/2J MGP_DBA2J_G0026256
 protein coding gene Chr2:122446317-122486868 (-)
FVB/NJ MGP_FVBNJ_G0026220
 protein coding gene Chr2:121136998-121175456 (-)
LP/J MGP_LPJ_G0026361
 protein coding gene Chr2:128488647-128528756 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026241
 protein coding gene Chr2:141298434-141339062 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026899
 protein coding gene Chr2:126579188-126619749 (-)
PWK/PhJ MGP_PWKPhJ_G0025340
 protein coding gene Chr2:121983913-122023824 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025141
 protein coding gene Chr2:125661753-125701840 (-)
WSB/EiJ MGP_WSBEiJ_G0025677
 protein coding gene Chr2:127482438-127525268 (-)



Homology
more
  • Human Ortholog
    MYEF2, myelin expression factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYEF2, myelin expression factor 2
  • Synonyms
    HsT18564, MEF-2, MST156, MSTP156, myEF-2
  • Links
    NCBI Gene ID: 50804
    neXtProt AC: NX_Q9P2K5
    UniProt: Q9P2K5

  • Chr Location
    15q21.1; chr15:48134632-48178353 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    826
  • Tissues
    120
  • cDNA Data
    83
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027201 Ensembl Gene Model | MGI Sequence Detail 39034 C57BL/6J ±  kb
transcript ENSMUST00000152367 Ensembl | MGI Sequence Detail 2071 Not Applicable  
polypeptide ENSMUSP00000123088 Ensembl | MGI Sequence Detail 591 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    Genomic 1
    cDNA 86
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-26026
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:188791 van Riel B, et al., A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Mol Cell Biol. 2012 Oct;32(19):3814-22
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory