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Tm4sf1 Gene Detail
Summary
  • Symbol
    Tm4sf1
  • Name
    transmembrane 4 superfamily member 1
  • Synonyms
    12A8 target antigen, L6, L6 antigen, M3s1
  • Feature Type
    protein coding gene
  • IDs
    MGI:104678
    NCBI Gene: 17112
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:57193032-57209409 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 27.68 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    524 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104678
 protein coding gene Chr3:57193032-57295150 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027227
 protein coding gene Chr3:56071381-56088464 (-)
A/J MGP_AJ_G0027187
 protein coding gene Chr3:54326021-54342427 (-)
AKR/J MGP_AKRJ_G0027157
 protein coding gene Chr3:55443475-55459876 (-)
BALB/cJ MGP_BALBcJ_G0027200
 protein coding gene Chr3:54170182-54186539 (-)
C3H/HeJ MGP_C3HHeJ_G0026943
 protein coding gene Chr3:55649278-55669678 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027646
 protein coding gene Chr3:58150528-58166971 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025004
 protein coding gene Chr3:50747636-50764433 (-)
CAST/EiJ MGP_CASTEiJ_G0026395
 protein coding gene Chr3:55798000-55814434 (-)
CBA/J MGP_CBAJ_G0026919
 protein coding gene Chr3:60066957-60087017 (-)
DBA/2J MGP_DBA2J_G0027053
 protein coding gene Chr3:53843121-53857890 (-)
FVB/NJ MGP_FVBNJ_G0027021
 protein coding gene Chr3:52819824-52836335 (-)
LP/J MGP_LPJ_G0027165
 protein coding gene Chr3:56810200-56826560 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027039
 protein coding gene Chr3:64161289-64178400 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027704
 protein coding gene Chr3:55393483-55409860 (-)
PWK/PhJ MGP_PWKPhJ_G0026127
 protein coding gene Chr3:53491474-53507863 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025940
 protein coding gene Chr3:55086680-55102812 (-)
WSB/EiJ MGP_WSBEiJ_G0026469
 protein coding gene Chr3:55484888-55501316 (-)



Homology
more
  • Human Ortholog
    TM4SF1, transmembrane 4 L six family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM4SF1, transmembrane 4 L six family member 1
  • Synonyms
    H-L6, L6, M3S1, TAAL6
  • Links
    NCBI Gene ID: 4071
    neXtProt AC: NX_P30408
    UniProt: P30408

  • Chr Location
    3q25.1; chr3:149369022-149377692 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    14
  • cDNA Data
    145
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027800 Ensembl Gene Model | MGI Sequence Detail 16378 C57BL/6J ±  kb
transcript ENSMUST00000196979 Ensembl | MGI Sequence Detail 3372 Not Applicable  
polypeptide ENSMUSP00000143652 Ensembl | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 147
    cDNA 145
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-27041
References
more
  • Summaries
    All 46
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory