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Psmb1 Gene Detail
Summary
  • Symbol
    Psmb1
  • Name
    proteasome (prosome, macropain) subunit, beta type 1
  • Synonyms
    Lmpc5
  • Feature Type
    protein coding gene
  • IDs
    MGI:104884
    NCBI Gene: 19170
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:15695983-15718538 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 8.95 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    674 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104884
 protein coding gene Chr17:15695283-15720013 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023174
 protein coding gene Chr17:13320840-13341333 (-)
A/J MGP_AJ_G0023140
 protein coding gene Chr17:13066301-13085948 (-)
AKR/J MGP_AKRJ_G0023110
 protein coding gene Chr17:13031603-13050983 (-)
BALB/cJ MGP_BALBcJ_G0023140
 protein coding gene Chr17:13018111-13038928 (-)
C3H/HeJ MGP_C3HHeJ_G0022901
 protein coding gene Chr17:13220724-13240791 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023583
 protein coding gene Chr17:13931407-13950566 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021095
 protein coding gene Chr17:11086294-11106072 (-)
CAST/EiJ MGP_CASTEiJ_G0022418
 protein coding gene Chr17:13135824-13153501 (-)
CBA/J MGP_CBAJ_G0022877
 protein coding gene Chr17:14384727-14403388 (-)
DBA/2J MGP_DBA2J_G0023010
 protein coding gene Chr17:12789012-12808943 (-)
FVB/NJ MGP_FVBNJ_G0022976
 protein coding gene Chr17:12633980-12653131 (-)
LP/J MGP_LPJ_G0023084
 protein coding gene Chr17:13314166-13336815 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022999
 protein coding gene Chr17:13919558-13939512 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023619
 protein coding gene Chr17:13270861-13292249 (-)
PWK/PhJ MGP_PWKPhJ_G0022166
 protein coding gene Chr17:12279405-12298339 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021996
 protein coding gene Chr17:12226409-12246210 (-)
WSB/EiJ MGP_WSBEiJ_G0022477
 protein coding gene Chr17:13594994-13613497 (-)



Homology
more
  • Human Ortholog
    PSMB1, proteasome 20S subunit beta 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMB1, proteasome 20S subunit beta 1
  • Synonyms
    HC5, NEDMHAL, PMSB1, PSC5
  • Links
    NCBI Gene ID: 5689
    neXtProt AC: NX_P20618
    UniProt: P20618

  • Chr Location
    6q27; chr6:170535120-170553307 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    36
  • cDNA Data
    284
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19170 NCBI Gene Model | MGI Sequence Detail 22556 C57BL/6J ±  kb
transcript NM_011185 RefSeq | MGI Sequence Detail 1036 C57BL/6  
polypeptide O09061 UniProt | EBI | MGI Sequence Detail 240 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 293
    Genomic 9
    cDNA 284

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-11826, MGD-MRK-29037, MGI:2146756, MGI:2147141
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:4568 Woodward EC, et al., Chromosomal mapping of the non-MHC linked proteasome genes. J Immunol. 1993;150(8):43A (Abstr.)
  • Latest
    J:351297 Ge T, et al., Coiled-coil domain containing 159 is required for spermatid head and tail assembly in mice. Biol Reprod. 2024 May 9;110(5):877-894
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory