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Sf3a2 Gene Detail
Summary
  • Symbol
    Sf3a2
  • Name
    splicing factor 3a, subunit 2
  • Synonyms
    66kDa, PRP11, Sap62, SFA66
  • Feature Type
    protein coding gene
  • IDs
    MGI:104912
    NCBI Gene: 20222
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80634569-80640756 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    165 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104912
 protein coding gene Chr10:80634032-80640758 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017519
 protein coding gene Chr10:81451193-81457919 (+)
A/J MGP_AJ_G0017497
 protein coding gene Chr10:78589781-78596570 (+)
AKR/J MGP_AKRJ_G0017458
 protein coding gene Chr10:80743894-80750620 (+)
BALB/cJ MGP_BALBcJ_G0017459
 protein coding gene Chr10:78803668-78810394 (+)
C3H/HeJ MGP_C3HHeJ_G0017282
 protein coding gene Chr10:80829358-80836084 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017913
 protein coding gene Chr10:84254843-84261569 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015602
 protein coding gene Chr10:74799292-74805577 (+)
CAST/EiJ MGP_CASTEiJ_G0016849
 protein coding gene Chr10:81057351-81063634 (+)
CBA/J MGP_CBAJ_G0017254
 protein coding gene Chr10:87522608-87529334 (+)
DBA/2J MGP_DBA2J_G0017360
 protein coding gene Chr10:77788517-77795243 (+)
FVB/NJ MGP_FVBNJ_G0017354
 protein coding gene Chr10:77020073-77026799 (+)
LP/J MGP_LPJ_G0017431
 protein coding gene Chr10:81915899-81922625 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017380
 protein coding gene Chr10:89441099-89447825 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017954
 protein coding gene Chr10:80737616-80744342 (+)
PWK/PhJ MGP_PWKPhJ_G0016630
 protein coding gene Chr10:77677264-77684180 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016420
 protein coding gene Chr10:79683803-79690042 (+)
WSB/EiJ MGP_WSBEiJ_G0016909
 protein coding gene Chr10:80771876-80778601 (+)



Homology
more
  • Human Ortholog
    SF3A2, splicing factor 3a subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SF3A2, splicing factor 3a subunit 2
  • Synonyms
    PRP11, PRPF11, SAP62, SF3a66
  • Links
    NCBI Gene ID: 8175
    neXtProt AC: NX_Q15428
    UniProt: Q15428

  • Chr Location
    19p13.3; chr19:2236824-2248655 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    757
  • Tissues
    24
  • cDNA Data
    51
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20222 NCBI Gene Model | MGI Sequence Detail 6188 C57BL/6J ±  kb
transcript NM_013651 RefSeq | MGI Sequence Detail 1674 ZRU/MplStud  
polypeptide Q62203 UniProt | EBI | MGI Sequence Detail 475 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    Genomic 2
    cDNA 54
    Primer pair 4

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-29066, MGI:2143796
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:299860 Jin L, et al., STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells. Nat Commun. 2020 Nov 23;11(1):5941
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory