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Zp3r Gene Detail
Summary
  • Symbol
    Zp3r
  • Name
    zona pellucida 3 receptor
  • Synonyms
    SP56
  • Feature Type
    protein coding gene
  • IDs
    MGI:104965
    NCBI Gene: 22789
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:130504450-130557358 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 56.89 cM, cytoband E-F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    356 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104965
 protein coding gene Chr1:130474847-130557371 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016435
 protein coding gene Chr1:133967743-134015572 (-)
A/J MGP_AJ_G0016418
 protein coding gene Chr1:129012866-129063818 (-)
AKR/J MGP_AKRJ_G0016383
 protein coding gene Chr1:132806536-132859169 (-)
BALB/cJ MGP_BALBcJ_G0016378
 protein coding gene Chr1:129351151-129396746 (-)
C3H/HeJ MGP_C3HHeJ_G0016204
 protein coding gene Chr1:132953886-133000997 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016839
 protein coding gene Chr1:138954584-139005747 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014553
 protein coding gene Chr1:122170435-122216536 (-)
CAST/EiJ MGP_CASTEiJ_G0015784
 protein coding gene Chr1:131940974-131989918 (-)
CBA/J MGP_CBAJ_G0016176
 protein coding gene Chr1:143729730-143789249 (-)
DBA/2J MGP_DBA2J_G0016283
 protein coding gene Chr1:127975579-128027496 (-)
FVB/NJ MGP_FVBNJ_G0016282
 protein coding gene Chr1:126627611-126672070 (-)
LP/J MGP_LPJ_G0016354
 protein coding gene Chr1:135274870-135331455 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016307
 protein coding gene Chr1:149514982-149562246 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016875
 protein coding gene Chr1:132576146-132630475 (-)
PWK/PhJ MGP_PWKPhJ_G0015570
 protein coding gene Chr1:126950386-126995685 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015357
 protein coding gene Chr1:131505573-131550313 (-)
WSB/EiJ MGP_WSBEiJ_G0015846
 protein coding gene Chr1:132536739-132586492 (-)



Homology
more
  • Human Ortholog
    C4BPA, complement component 4 binding protein alpha
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C4BPA, complement component 4 binding protein alpha
  • Synonyms
    C4BP, PRP
  • Links
    NCBI Gene ID: 722
    neXtProt AC: NX_P04003
    UniProt: P04003

  • Chr Location
    1q32.2; chr1:207104233-207144972 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human C4BPA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    6 phenotype references
Mice homozygous for a knock-out allele exhibit normal fertility and sperm morphology and physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    15
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042554 Ensembl Gene Model | MGI Sequence Detail 52909 C57BL/6J ±  kb
transcript ENSMUST00000039862 Ensembl | MGI Sequence Detail 2042 Not Applicable  
polypeptide ENSMUSP00000045443 Ensembl | MGI Sequence Detail 579 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 1
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-31038, MGI:2138528
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Gene Ontology 15
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:334700 Bizkarguenaga M, et al., Zona Pellucida sperm-binding protein 3 receptor distribution during Gopc(-/-) globozoospermic spermatogenesis. Microsc Res Tech. 2022 Apr;85(4):1454-1464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory