elap Gene Detail

Summary

• Symbol
  elap
• Name
  eye lens aplasia
• Synonyms
  lap

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:105916
  NCBI Gene: 13708
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Homozygotes for a spontaneous mutation exhibit eye defects including microphthalmia, aphakia, absence of the anterior chamber, dystrophy of the cornea and vitreous body, and retinal disorganization.

Sequences &
Gene Models

• NCBI Gene
  13708

Other
Accession IDs

MGD-MRK-33296, MGD-MRK-33593

References

• Summaries
  All 7

  Phenotypes 3
• Earliest
  J:23892 Aso S, et al., Lens aplasia: a new mutation producing lens abnormality in the mouse. Lab Anim Sci. 1995 Feb;45(1):41-6
• Latest
  J:238745 Nishikii H, et al., DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease. Blood. 2016 Dec 15;128(24):2846-2858