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Adam26a Gene Detail
Summary
  • Symbol
    Adam26a
  • Name
    ADAM metallopeptidase domain 26A
  • Synonyms
    Adam26, Dtgn4
  • Feature Type
    protein coding gene
  • IDs
    MGI:105985
    NCBI Gene: 13525
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:44021315-44029744 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 24.02 cM, cytoband B1.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105985
 protein coding gene Chr8:44021310-44029744 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0033550
 protein coding gene Chr8:40969852-40996424 (-)
AKR/J MGP_AKRJ_G0033474
 protein coding gene Chr8:42033662-42060125 (-)
BALB/cJ MGP_BALBcJ_G0033546
 protein coding gene Chr8:41016935-41084022 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0034061
 protein coding gene Chr8:44056277-44058722 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0032583
 protein coding gene Chr8:41981749-41983865 (-)
CBA/J MGP_CBAJ_G0033233
 protein coding gene Chr8:45876693-45885373 (-)
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0033374
 protein coding gene Chr8:45988261-45997961 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034080
 protein coding gene Chr8:42286213-42294503 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0032126
 protein coding gene Chr8:41423721-41438044 (-)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    7
  • cDNA Data
    4
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000048516 Ensembl Gene Model | MGI Sequence Detail 8430 C57BL/6J ±  kb
    transcript ENSMUST00000049577 Ensembl | MGI Sequence Detail 2489 Not Applicable  
    polypeptide ENSMUSP00000058256 Ensembl | MGI Sequence Detail 697 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-33665
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:30468 Weskamp G, et al., A family of cellular proteins related to snake venom disintegrins. Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2748-51
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory