Lurap1l MGI Mouse Gene Detail - MGI:106510 - leucine rich adaptor protein 1-like

Symbol

Lurap1l
Name

leucine rich adaptor protein 1-like
Synonyms

1110029A09Rik, D4Bwg0951e, WI-13707

Feature Type

protein coding gene
IDs

MGI:106510
NCBI Gene: 52829
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr4:80828923-80872538 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 37.91 cM
Mapping Data

3 experiments

SNPs within 2kb

1358 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_106510	protein coding gene	Chr4:80828883-80873865 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028396	protein coding gene	Chr4:80471282-80515419 (+)
A/J	MGP_AJ_G0028357	protein coding gene	Chr4:77679031-77721270 (+)
AKR/J	MGP_AKRJ_G0028306	protein coding gene	Chr4:79650516-79696664 (+)
BALB/cJ	MGP_BALBcJ_G0028377	protein coding gene	Chr4:77937610-77983752 (+)
C3H/HeJ	MGP_C3HHeJ_G0028092	protein coding gene	Chr4:80270393-80315894 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028816	protein coding gene	Chr4:83623095-83676359 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026116	protein coding gene	Chr4:73700547-73744406 (+)
CAST/EiJ	MGP_CASTEiJ_G0027533	protein coding gene	Chr4:78207072-78263856 (+)
CBA/J	MGP_CBAJ_G0028061	protein coding gene	Chr4:86243016-86293742 (+)
DBA/2J	MGP_DBA2J_G0028210	protein coding gene	Chr4:77434345-77486225 (+)
FVB/NJ	MGP_FVBNJ_G0028176	protein coding gene	Chr4:76430868-76475524 (+)
LP/J	MGP_LPJ_G0028310	protein coding gene	Chr4:80794009-80840095 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028205	protein coding gene	Chr4:91297577-91343752 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028853	protein coding gene	Chr4:79738144-79781002 (+)
PWK/PhJ	MGP_PWKPhJ_G0027256	protein coding gene	Chr4:75798730-75845849 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027081	protein coding gene	Chr4:77243845-77290484 (+)
WSB/EiJ	MGP_WSBEiJ_G0027609	protein coding gene	Chr4:79909082-79952967 (+)

Human Ortholog

LURAP1L, leucine rich adaptor protein 1 like

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

LURAP1L, leucine rich adaptor protein 1 like
Synonyms

bA3L8.2, C9orf150, HYST0841, LRAP35b
Links

HGNC:31452

NCBI Gene ID: 286343

neXtProt AC: NX_Q8IV03

UniProt: Q8IV03
Chr Location

9p23; chr9:12775020-12823060 (+) GRCh38

MGI Vertebrate Homology

Lurap1l stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: LURAP1L
Gene Tree

Lurap1l

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

2
Endonuclease-mediated

2
Gene trapped

1
Radiation induced

1
Genomic Mutations

3 involving Lurap1l
Incidental Mutations

CvDC
Find Mice (IMSR)

13 strains or lines available

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All GO Annotations

2
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

795
Tissues

12
cDNA Data

4
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase lurap1l

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All Sequences

35
RefSeq

2
UniProt

1
CCDS

CCDS18291.1

Ensembl

ENSMUSG00000048706 (Evidence)
NCBI Gene

52829

			Length	Strain/Species	Flank
genomic	52829	NCBI Gene Model \| MGI Sequence Detail	43616	C57BL/6J	± kb
transcript	NM_026821	RefSeq \| MGI Sequence Detail	1699	ZRU/MplStud
polypeptide	Q8K2P1	UniProt \| EBI \| MGI Sequence Detail	221	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000031403 leucine rich adaptor protein 1-like

(term hierarchy)
InterPro Domains

IPR037443 Leucine rich adaptor protein 1

IPR039499 Leucine rich adaptor protein 1/25

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All nucleic 5

cDNA 4

Primer pair 1

Microarray probesets 5

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MGD-MRK-34204, MGI:1353480, MGI:1915967, MGI:2140524, MGI:2140531

Summaries

All 34

Developmental Gene Expression 2

Gene Ontology 2

Phenotypes 8
Earliest

J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Lurap1l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr37670	Chr4:80828907-80828922 (+)	-8 bp
Tssr37671	Chr4:80829081-80829096 (+)	166 bp
Tssr37672	Chr4:80850378-80850382 (+)	21,457 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24