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Cnot11 Gene Detail
Summary
  • Symbol
    Cnot11
  • Name
    CCR4-NOT transcription complex, subunit 11
  • Synonyms
    2410015L18Rik, D1Bwg0212e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106580
    NCBI Gene: 52846
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:39574782-39585962 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 18.31 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    307 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106580
 protein coding gene Chr1:39574073-39585970 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015958
 protein coding gene Chr1:38280772-38293505 (+)
A/J MGP_AJ_G0015942
 protein coding gene Chr1:37210682-37222712 (+)
AKR/J MGP_AKRJ_G0015897
 protein coding gene Chr1:37713785-37725631 (+)
BALB/cJ MGP_BALBcJ_G0015896
 protein coding gene Chr1:36858726-36870275 (+)
C3H/HeJ MGP_C3HHeJ_G0015729
 protein coding gene Chr1:37973004-37987424 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016349
 protein coding gene Chr1:39873015-39890407 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014071
 protein coding gene Chr1:34175329-34186401 (+)
CAST/EiJ MGP_CASTEiJ_G0015310
 protein coding gene Chr1:37852301-37866066 (+)
CBA/J MGP_CBAJ_G0015701
 protein coding gene Chr1:41026718-41042774 (+)
DBA/2J MGP_DBA2J_G0015802
 protein coding gene Chr1:36495001-36506796 (+)
FVB/NJ MGP_FVBNJ_G0015804
 protein coding gene Chr1:36030178-36041934 (+)
LP/J MGP_LPJ_G0015872
 protein coding gene Chr1:38619253-38631887 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015824
 protein coding gene Chr1:43079658-43091574 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016396
 protein coding gene Chr1:37830902-37843614 (+)
PWK/PhJ MGP_PWKPhJ_G0015093
 protein coding gene Chr1:36308037-36323117 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014875
 protein coding gene Chr1:37763144-37780309 (+)
WSB/EiJ MGP_WSBEiJ_G0015372
 protein coding gene Chr1:37777564-37797295 (+)



Homology
more
  • Human Ortholog
    CNOT11, CCR4-NOT transcription complex subunit 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNOT11, CCR4-NOT transcription complex subunit 11
  • Synonyms
    C2orf29, C40
  • Links
    NCBI Gene ID: 55571
    neXtProt AC: NX_Q9UKZ1
    UniProt: Q9UKZ1

  • Chr Location
    2q11.2; chr2:101252886-101270316 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Cnot11
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 52846 NCBI Gene Model | MGI Sequence Detail 11181 C57BL/6J ±  kb
transcript NM_028043 RefSeq | MGI Sequence Detail 3306 ZRU/MplStud  
polypeptide Q9CWN7 UniProt | EBI | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000039400 CCR4-NOT transcription complex subunit 11
    (term hierarchy)
  • InterPro Domains
    IPR019312 CCR4-NOT transcription complex subunit 11
  • GlyGen
    Q9CWN7 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-34274, MGI:1919242
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory