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Vdac2 Gene Detail
Summary
  • Symbol
    Vdac2
  • Name
    voltage-dependent anion channel 2
  • Synonyms
    Vdac6
  • Feature Type
    protein coding gene
  • IDs
    MGI:106915
    NCBI Gene: 22334
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:21881629-21895947 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 11.91 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    412 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106915
 protein coding gene Chr14:21875306-21895947 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021056
 protein coding gene Chr14:14677968-14696163 (+)
A/J MGP_AJ_G0021005
 protein coding gene Chr14:14293229-14307833 (+)
AKR/J MGP_AKRJ_G0020982
 protein coding gene Chr14:14857851-14877333 (+)
BALB/cJ MGP_BALBcJ_G0021008
 protein coding gene Chr14:14398085-14413819 (+)
C3H/HeJ MGP_C3HHeJ_G0020792
 protein coding gene Chr14:14782629-14797084 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021441
 protein coding gene Chr14:15159221-15173806 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019009
 protein coding gene Chr14:14610471-14624550 (+)
CAST/EiJ MGP_CASTEiJ_G0020316
 protein coding gene Chr14:14596220-14611778 (+)
CBA/J MGP_CBAJ_G0020758
 protein coding gene Chr14:15940938-15958360 (+)
DBA/2J MGP_DBA2J_G0020881
 protein coding gene Chr14:14126003-14140668 (+)
FVB/NJ MGP_FVBNJ_G0020864
 protein coding gene Chr14:14013499-14028081 (+)
LP/J MGP_LPJ_G0020957
 protein coding gene Chr14:14887303-14903351 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020890
 protein coding gene Chr14:15683237-15700818 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021474
 protein coding gene Chr14:14638934-14654812 (+)
PWK/PhJ MGP_PWKPhJ_G0020065
 protein coding gene Chr14:13714294-13730558 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019887
 protein coding gene Chr14:14454063-14469289 (+)
WSB/EiJ MGP_WSBEiJ_G0020372
 protein coding gene Chr14:14635228-14652078 (+)



Homology
more
  • Human Ortholog
    VDAC2, voltage dependent anion channel 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VDAC2, voltage dependent anion channel 2
  • Synonyms
    POR
  • Links
    NCBI Gene ID: 7417
    neXtProt AC: NX_P45880
    UniProt: P45880

  • Chr Location
    10q22.2; chr10:75210154-75231448 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    49
  • GO References
    18
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    96
  • cDNA Data
    329
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22334 NCBI Gene Model | MGI Sequence Detail 14319 C57BL/6J ±  kb
    transcript NM_011695 RefSeq | MGI Sequence Detail 1662 ZRU/MplStud  
    polypeptide Q60930 UniProt | EBI | MGI Sequence Detail 295 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000017281 voltage-dependent anion-selective channel protein 2
      (term hierarchy)
    • InterPro Domains
      IPR027246 Eukaryotic porin/Tom40
      IPR023614 Porin domain superfamily
      IPR001925 Porin, eukaryotic type
    • GlyGen
      Q60930 4 sites, 3 N-linked glycans (3 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 334
      Genomic 3
      cDNA 329
      Primer pair 1
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-35376
    References
    more
    • Summaries
      All 66
      Developmental Gene Expression 6
      Gene Ontology 18
      Phenotypes 10
    • Earliest
      J:32840 Sampson MJ, et al., Isolation, characterization, and mapping of two mouse mitochondrial voltage-dependent anion channel isoforms. Genomics. 1996 Apr 15;33(2):283-8
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory