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Srp14 Gene Detail
Summary
  • Symbol
    Srp14
  • Name
    signal recognition particle 14
  • Synonyms
    14kDa, (homologous Alu RNA binding protein)
  • Feature Type
    protein coding gene
  • IDs
    MGI:107169
    NCBI Gene: 20813
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:118306324-118310177 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 59.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107169
 protein coding gene Chr2:118306324-118310192 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026315
 protein coding gene Chr2:121161500-121164629 (-)
A/J MGP_AJ_G0026276
 protein coding gene Chr2:116246143-116249273 (-)
AKR/J MGP_AKRJ_G0026255
 protein coding gene Chr2:119505849-119508977 (-)
BALB/cJ MGP_BALBcJ_G0026289
 protein coding gene Chr2:116500902-116504032 (-)
C3H/HeJ MGP_C3HHeJ_G0026035
 protein coding gene Chr2:119958905-119962023 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026736
 protein coding gene Chr2:125166567-125170428 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024116
 protein coding gene Chr2:111292653-111296583 (-)
CAST/EiJ MGP_CASTEiJ_G0025497
 protein coding gene Chr2:120272548-120275660 (-)
CBA/J MGP_CBAJ_G0026011
 protein coding gene Chr2:129591154-129594270 (-)
DBA/2J MGP_DBA2J_G0026150
 protein coding gene Chr2:115665418-115668547 (-)
FVB/NJ MGP_FVBNJ_G0026112
 protein coding gene Chr2:114492766-114495899 (-)
LP/J MGP_LPJ_G0026251
 protein coding gene Chr2:121485718-121490484 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026131
 protein coding gene Chr2:133959956-133963080 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026791
 protein coding gene Chr2:119626320-119629436 (-)
PWK/PhJ MGP_PWKPhJ_G0025233
 protein coding gene Chr2:115219261-115222423 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025032
 protein coding gene Chr2:118785230-118789142 (-)
WSB/EiJ MGP_WSBEiJ_G0025566
 protein coding gene Chr2:120447438-120450562 (-)



Homology
more
  • Human Ortholog
    SRP14, signal recognition particle 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRP14, signal recognition particle 14
  • Synonyms
    ALURBP
  • Links
    NCBI Gene ID: 6727
    neXtProt AC: NX_P37108
    UniProt: P37108

  • Chr Location
    15q15.1; chr15:40035690-40039202 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Srp14
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    746
  • Tissues
    8
  • cDNA Data
    178
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20813 NCBI Gene Model | MGI Sequence Detail 3854 C57BL/6J ±  kb
transcript NM_009273 RefSeq | MGI Sequence Detail 790 C57BL/6  
polypeptide P16254 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015623 signal recognition particle 14 kDa protein
    (term hierarchy)
  • PDB
    1914
  • InterPro Domains
    IPR003210 Signal recognition particle, SRP14 subunit
    IPR009018 Signal recognition particle, SRP9/SRP14 subunit
  • GlyGen
    P16254 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 180
    cDNA 178
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-35630, MGI:2139363
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory