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Cyp2b19 Gene Detail
Summary
  • Symbol
    Cyp2b19
  • Name
    cytochrome P450, family 2, subfamily b, polypeptide 19
  • Feature Type
    protein coding gene
  • IDs
    MGI:107303
    NCBI Gene: 13090
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:26456567-26472055 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 15.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    472 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107303
 protein coding gene Chr7:26456567-26472055 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031890
 protein coding gene Chr7:25335654-25352779 (+)
A/J MGP_AJ_G0031869
 protein coding gene Chr7:24715786-24731909 (+)
AKR/J MGP_AKRJ_G0031799
 protein coding gene Chr7:25346110-25361607 (+)
BALB/cJ MGP_BALBcJ_G0031875
 protein coding gene Chr7:24920474-24935806 (+)
C3H/HeJ MGP_C3HHeJ_G0031597
 protein coding gene Chr7:25759522-25776159 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032337
 protein coding gene Chr7:26190888-26206203 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029392
 protein coding gene Chr7:26019160-26034009 (+)
CAST/EiJ MGP_CASTEiJ_G0030933
 protein coding gene Chr7:19044056-19059394 (+)
CBA/J MGP_CBAJ_G0031562
 protein coding gene Chr7:27211534-27230692 (+)
DBA/2J MGP_DBA2J_G0031714
 protein coding gene Chr7:24547767-24564697 (+)
FVB/NJ MGP_FVBNJ_G0031669
 protein coding gene Chr7:24639787-24655065 (+)
LP/J MGP_LPJ_G0031793
 protein coding gene Chr7:25608499-25623938 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031703
 protein coding gene Chr7:26875921-26892056 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032371
 protein coding gene Chr7:24928170-24944024 (+)
PWK/PhJ MGP_PWKPhJ_G0030657
 protein coding gene Chr7:19499450-19516235 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030488
 protein coding gene Chr7:16048082-16064289 (+)
WSB/EiJ MGP_WSBEiJ_G0031038
 protein coding gene Chr7:25205940-25221663 (+)



Homology
more
  • Human Ortholog
    CYP2B6, cytochrome P450 family 2 subfamily B member 6
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2B6, cytochrome P450 family 2 subfamily B member 6
  • Synonyms
    CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
  • Links
    NCBI Gene ID: 1555
    neXtProt AC: NX_P20813
    UniProt: P20813

  • Chr Location
    19q13.2; chr19:40991282-41018398 (+)  GRCh38
Human Diseases
more
  • Diseases
    7 with human CYP2B6 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    852
  • Tissues
    126
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13090 NCBI Gene Model | MGI Sequence Detail 15489 C57BL/6J ±  kb
transcript NM_007814 RefSeq | MGI Sequence Detail 2765 C57BL/6  
polypeptide O55071 UniProt | EBI | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 15
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35769
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:45291 Keeney DS, The novel skin-specific cytochrome p450 Cyp2b19 maps to proximal chromosome 7 in the mouse, near a cluster of Cyp2 family genes. Genomics. 1998 NOV 1;53(3):417-419
  • Latest
    J:341642 Schwartz B, et al., ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory