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Ube2e1 Gene Detail
Summary
  • Symbol
    Ube2e1
  • Name
    ubiquitin-conjugating enzyme E2E 1
  • Synonyms
    Ubce5, ubcM2, UbcM3
  • Feature Type
    protein coding gene
  • IDs
    MGI:107411
    NCBI Gene: 22194
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:4137852-4186967 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 7.08 cM, cytoband A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    999 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107411
 protein coding gene Chr14:4137837-4186974 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021021
 protein coding gene Chr14:10894119-10948383 (-)
A/J MGP_AJ_G0020970
 protein coding gene Chr14:10579017-10628098 (-)
AKR/J MGP_AKRJ_G0020947
 protein coding gene Chr14:10895608-10947506 (-)
BALB/cJ MGP_BALBcJ_G0020973
 protein coding gene Chr14:10640407-10699536 (-)
C3H/HeJ MGP_C3HHeJ_G0020757
 protein coding gene Chr14:10975230-11034442 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021406
 protein coding gene Chr14:11289467-11340772 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018975
 protein coding gene Chr14:11087016-11132786 (-)
CAST/EiJ MGP_CASTEiJ_G0020280
 protein coding gene Chr14:10839596-10890739 (-)
CBA/J MGP_CBAJ_G0020723
 protein coding gene Chr14:11764999-11832387 (-)
DBA/2J MGP_DBA2J_G0020846
 protein coding gene Chr14:10477908-10528949 (-)
FVB/NJ MGP_FVBNJ_G0020829
 protein coding gene Chr14:10348786-10397667 (-)
LP/J MGP_LPJ_G0020922
 protein coding gene Chr14:10960546-11013210 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020855
 protein coding gene Chr14:11648466-11701049 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021438
 protein coding gene Chr14:10778812-10832843 (-)
PWK/PhJ MGP_PWKPhJ_G0020031
 protein coding gene Chr14:10538336-10588543 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019851
 protein coding gene Chr14:10909095-10964971 (-)
WSB/EiJ MGP_WSBEiJ_G0020336
 protein coding gene Chr14:10830448-10883383 (-)



Homology
more
  • Human Ortholog
    UBE2E1, ubiquitin conjugating enzyme E2 E1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2E1, ubiquitin conjugating enzyme E2 E1
  • Synonyms
    UBCH6
  • Links
    NCBI Gene ID: 7324
    neXtProt AC: NX_P51965
    UniProt: P51965

  • Chr Location
    3p24.2; chr3:23805955-23891640 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    946
  • Tissues
    110
  • cDNA Data
    58
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22194 NCBI Gene Model | MGI Sequence Detail 49116 C57BL/6J ±  kb
transcript NM_009455 RefSeq | MGI Sequence Detail 1386 C57BL/6  
polypeptide P52482 UniProt | EBI | MGI Sequence Detail 193 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 58
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35880
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:31581 Matuschewski K, et al., Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions. J Biol Chem. 1996 Feb 2;271(5):2789-94
  • Latest
    J:267520 Pasupala N, et al., OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination. J Biol Chem. 2018 Nov 23;293(47):18285-18295
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory