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Ube2e3 Gene Detail
Summary
  • Symbol
    Ube2e3
  • Name
    ubiquitin-conjugating enzyme E2E 3
  • Synonyms
    Ubce4, ubcM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107412
    NCBI Gene: 22193
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:78698468-78751637 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 47.15 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1049 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107412
 protein coding gene Chr2:78698468-78759132 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025875
 protein coding gene Chr2:79358577-79420022 (+)
A/J MGP_AJ_G0025852
 protein coding gene Chr2:76308512-76364717 (+)
AKR/J MGP_AKRJ_G0025821
 protein coding gene Chr2:78308737-78363731 (+)
BALB/cJ MGP_BALBcJ_G0025848
 protein coding gene Chr2:76442234-76495804 (+)
C3H/HeJ MGP_C3HHeJ_G0025607
 protein coding gene Chr2:78530431-78586833 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026294
 protein coding gene Chr2:81703654-81760248 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023697
 protein coding gene Chr2:73588845-73642088 (+)
CAST/EiJ MGP_CASTEiJ_G0025069
 protein coding gene Chr2:78951804-79011685 (+)
CBA/J MGP_CBAJ_G0025588
 protein coding gene Chr2:84638579-84699292 (+)
DBA/2J MGP_DBA2J_G0025719
 protein coding gene Chr2:75867585-75921655 (+)
FVB/NJ MGP_FVBNJ_G0025681
 protein coding gene Chr2:75240645-75293637 (+)
LP/J MGP_LPJ_G0025807
 protein coding gene Chr2:79248087-79308875 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025712
 protein coding gene Chr2:86521155-86580602 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026350
 protein coding gene Chr2:78471754-78529636 (+)
PWK/PhJ MGP_PWKPhJ_G0024812
 protein coding gene Chr2:75810738-75867643 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024618
 protein coding gene Chr2:78751259-78806723 (+)
WSB/EiJ MGP_WSBEiJ_G0025138
 protein coding gene Chr2:79093041-79148258 (+)



Homology
more
  • Human Ortholog
    UBE2E3, ubiquitin conjugating enzyme E2 E3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2E3, ubiquitin conjugating enzyme E2 E3
  • Synonyms
    UBCH9, UbcM2
  • Links
    NCBI Gene ID: 10477
    neXtProt AC: NX_Q969T4
    UniProt: Q969T4

  • Chr Location
    2q31.3; chr2:180967248-181076585 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027011 Ensembl Gene Model | MGI Sequence Detail 53170 C57BL/6J ±  kb
transcript ENSMUST00000121433 Ensembl | MGI Sequence Detail 1235 Not Applicable  
polypeptide ENSMUSP00000113463 Ensembl | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-35881
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:31581 Matuschewski K, et al., Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions. J Biol Chem. 1996 Feb 2;271(5):2789-94
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory